Domestic animals can be cloned using techniques such as embryo splitting and nuclear
transfer to produce genetically identical individuals. Although embryo splitting is limited to …

Cloning by nuclear transfer using mammalian somatic cells has enormous potential
application. However, somatic cloning has been inefficient in all species in which live clones …

Somatic nuclear transfer (NT) in cattle is often complicated by fetal oversize (ie, large
offspring syndrome), hydrallantois, and placentomegaly in late gestation. The aims of this …

Somatic cell nuclear transfer (SCNT), the technique commonly known as cloning, permits
transformation of a somatic cell into an undifferentiated zygote with the potential to develop …

As the demand for cloned embryos and offspring increases, the need arises for the
development of nuclear transfer procedures that are improved in both efficiency and ease of …

Somatic cell gene targeting combined with nuclear transfer cloning presents tremendous
potential for the creation of new, large-animal models of human diseases. Mouse disease …

The cloning syndrome is a continuum with the consequences of abnormal reprograming
manifest throughout gestation, the neo-natal period, and into adulthood in the cloned …

The significance of donor cell differentiation status for successful cloning by somatic cell
nuclear transfer (SCNT) is unclear. Here, we cloned a new species, red deer (Cervus …

The cloning of cattle by somatic cell nuclear transfer (NT) is associated with a high incidence
of abnormal placentation, excessive fluid accumulation in the fetal sacs (hydrops syndrome) …

An efficient animal cloning technology would provide many new opportunities for livestock
agriculture, human medicine, and animal conservation. Nuclear cloning involves the …