Boron neutron capture therapy: Current status and future perspectives

MA Dymova, SY Taskaev, VA Richter… - Cancer …, 2020 - Wiley Online Library
The development of new accelerators has given a new impetus to the development of new
drugs and treatment technologies using boron neutron capture therapy (BNCT). We …

Critical review, with an optimistic outlook, on Boron Neutron Capture Therapy (BNCT)

RL Moss - Applied Radiation and Isotopes, 2014 - Elsevier
The first BNCT trials took place in the USA in the early 1960's, yet BNCT is still far from
mainstream medicine. Nonetheless, in recent years, reported results in the treatment of head …

[HTML][HTML] Boron neutron capture therapy-a literature review

K Nedunchezhian, N Aswath… - Journal of clinical and …, 2016 - ncbi.nlm.nih.gov
Abstract Boron Neutron Capture Therapy (BNCT) is a radiation science which is emerging
as a hopeful tool in treating cancer, by selectively concentrating boron compounds in tumour …

Boron neutron capture therapy: a review of clinical applications

TD Malouff, DS Seneviratne, DK Ebner… - Frontiers in …, 2021 - frontiersin.org
Boron neutron capture therapy (BNCT) is an emerging treatment modality aimed at
improving the therapeutic ratio for traditionally difficult to treat tumors. BNCT utilizes …

A review of boron neutron capture therapy: Its history and current challenges

WH Jin, C Seldon, M Butkus… - … journal of particle …, 2022 - meridian.allenpress.com
Abstract Mechanism of Action External beam, whether with photons or particles, remains as
the most common type of radiation therapy. The main drawback is that radiation deposits …

[HTML][HTML] Glioblastoma treatment modalities besides surgery

H Zhang, R Wang, Y Yu, J Liu, T Luo, F Fan - Journal of Cancer, 2019 - ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) is commonly known as the most aggressive primary CNS
tumor in adults. The mean survival of it is 14 to 15 months, following the standard therapy …

Boron neutron capture therapy: clinical application and research progress

X Cheng, F Li, L Liang - Current Oncology, 2022 - mdpi.com
Boron neutron capture therapy (BNCT) is a binary modality that is used to treat a variety of
malignancies, using neutrons to irradiate boron-10 (10B) nuclei that have entered tumor …

Salvage boron neutron capture therapy for malignant brain tumor patients in compliance with emergency and compassionate use: Evaluation of 34 cases in Taiwan

YW Chen, YY Lee, CF Lin, PS Pan, JK Chen… - Biology, 2021 - mdpi.com
Simple Summary Although boron neutron capture therapy (BNCT) is a promising therapeutic
approach for malignant brain tumors, the optimal BNCT parameters for patients with life …

Key biological mechanisms involved in high-LET radiation therapies with a focus on DNA damage and repair

Z Nikitaki, A Velalopoulou, V Zanni, I Tremi… - Expert reviews in …, 2022 - cambridge.org
DNA damage and repair studies are at the core of the radiation biology field and represent
also the fundamental principles informing radiation therapy (RT). DNA damage levels are a …

Advancements in tumor targeting strategies for boron neutron capture therapy

MJ Luderer, P De La Puente, AK Azab - Pharmaceutical research, 2015 - Springer
Boron neutron capture therapy (BNCT) is a promising cancer therapy modality that utilizes
the nuclear capture reaction of epithermal neutrons by boron-10 resulting in a localized …