Molecular networking is a tandem mass spectrometry (MS/MS) data organizational
approach that has been recently introduced in the drug discovery, metabolomics, and …

Matrix‐dependent signal suppression or enhancement represents a major drawback in
quantitative analysis with liquid chromatography coupled to atmospheric pressure ionization …

Although, LC–MS is one of the most sensitive and selective analytical techniques, it often
suffers from matrix effects, especially when using ESI for analyzing extracts of complicated …

The structural elucidation of small molecules using mass spectrometry plays an important
role in modern life sciences and bioanalytical approaches. This review covers different soft …

Matrix effects can significantly impede the accuracy, sensitivity, and reliability of separation
techniques presenting a formidable challenge to the analytical process. It is crucial to …

Identification of unknowns is a bottleneck for large-scale untargeted analyses like
metabolomics or drug metabolite identification. Ion mobility-mass spectrometry (IM-MS) …

Sensitive and selective liquid chromatography–mass spectrometry (LC–MS) analysis is a
powerful and essential tool for metabolite identification in drug discovery and development …

The conventional pipeline for biomarker development involves a discovery phase, typically
conducted by mass spectrometry (MS), followed by validation and clinical application …

Identification of drug metabolites by liquid chromatography/mass spectrometry (LC/MS)
involves metabolite detection in biological matrixes and structural characterization based on …

An overview of liquid chromatography–mass spectrometry methods used for the
determination of trace organic contaminants in environmental samples is presented. Among …