Advances in vaccine development for Chlamydia trachomatis

TB Poston - Pathogens and Disease, 2024 - academic.oup.com
Chlamydia trachomatis is the most prevalent bacterial sexually transmitted infection globally.
Antibiotic treatment is highly effective, but infection is often asymptomatic resulting in most …

[HTML][HTML] Recent Advances in Oral Vaccines for Animals

K Zhong, X Chen, J Zhang, X Jiang, J Zhang… - Veterinary …, 2024 - mdpi.com
Simple Summary Oral vaccines provide a gentle and convenient way to prevent infectious
diseases in animals while inducing robust mucosal immunity that is particularly effective …

Irradiated whole cell Chlamydia vaccine confers significant protection in a murine genital tract challenge model

KC Broder, VY Matrosova, R Tkavc, EK Gaidamakova… - npj Vaccines, 2024 - nature.com
Chlamydia trachomatis infections are the most common bacterial STIs globally and can lead
to serious morbidity if untreated. Development of a killed, whole-cell vaccine has been …

IL-23 receptor signaling licenses group 3-like innate lymphoid cells to restrict a live-attenuated oral Chlamydia vaccine in the gut

Y He, Y Wang, R He, AM Abdelsalam… - Infection and …, 2023 - Am Soc Microbiol
An IFNγ-susceptible mutant of Chlamydia muridarum is attenuated in pathogenicity in the
genital tract and was recently licensed as an intr acellular O ral vaccine v ector or intrOv …

Preclinical screen for protection efficacy of chlamydial antigens that are immunogenic in humans

C Lu, J Wang, G Zhong - Infection and immunity, 2023 - Am Soc Microbiol
To search for subunit vaccine candidates, immunogenic chlamydial antigens identified in
humans were evaluated for protection against both infection and pathology in a mouse …

Differential polyvalent passive immune protection of egg yolk antibodies (IgY) against live and inactivated Vibrio fluvialis in fish

X Liu, H Xiao, P Cui, J Chen, J Chao, X Wu, J Lu… - Fish & Shellfish …, 2024 - Elsevier
Egg yolk antibodies (IgY) can be prepared in large quantities and economically, and have
potential value as polyvalent passive vaccines (against multiple bacteria) in aquaculture …

CRISPR/Cas9-edited duck enteritis virus expressing Pmp17G of Chlamydia psittaci induced protective immunity in ducklings

J Liu, Y Wang, N Tang, C He, F Li - Pathogens and Disease, 2024 - academic.oup.com
Chlamydia psittaci is threatening to the animal industry and human beings. Live attenuated
duck enteritis virus (DEV) is considered a good vaccine vector. In the present study, the …

Progress towards effective vaccines for Chlamydia trachomatis

AL Collar, KM Frietze - Current Opinion in Infectious Diseases, 2025 - journals.lww.com
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