Cortical networks are composed of glutamatergic excitatory projection neurons and local
GABAergic inhibitory interneurons that gate signal flow and sculpt network dynamics …

Sharp wave ripples (SPW‐Rs) represent the most synchronous population pattern in the
mammalian brain. Their excitatory output affects a wide area of the cortex and several …

The mystery of general anesthesia is that it specifically suppresses consciousness by
disrupting feedback signaling in the brain, even when feedforward signaling and basic …

Gamma band rhythms may synchronize distributed cell assemblies to facilitate information
transfer within and across brain areas, yet their underlying mechanisms remain hotly …

Systematic genetic access to GABAergic cell types will facilitate studying the function and
development of inhibitory circuitry. However, single gene-driven recombinase lines mark …

The proper construction of neural circuits requires the generation of diverse cell types, their
distribution to defined regions, and their specific and appropriate wiring. A major objective in …

γ-Aminobutyric acid (GABA) ergic inputs are strategically positioned to gate synaptic
integration along the dendritic arbor of pyramidal cells. However, their spatiotemporal …

Neural computation involves diverse types of GABAergic inhibitory interneurons that are
integrated with excitatory (E) neurons into precisely structured circuits. To understand how …

Many of our daily activities, such as riding a bike to work or reading a book in a noisy cafe,
and highly skilled activities, such as a professional playing a tennis match or a violin …

Sensory perception depends on neocortical computations that contextually adjust sensory
signals in different internal and environmental contexts. Neocortical layer 1 (L1) is the main …