[HTML][HTML] Epidemiology and biology of early onset colorectal cancer

A Venugopal, JM Carethers - EXCLI journal, 2022 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is the third leading cause of cancer-related mortality in men or
women in the United States. Average-risk screening that begins at age 50 years has …

[HTML][HTML] Molecular genetics of early-onset colorectal cancer

O Marx, M Mankarious, G Yochum - World Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Early-onset colorectal cancer (EOCRC) has been rising in global prevalence and incidence
over the past several decades. Environmental influences, including generational lifestyle …

Reduced expression of alanyl aminopeptidase is a robust biomarker of non‐familial adenomatous polyposis and non‐hereditary nonpolyposis colorectal cancer …

YJ Ha, YJ Shin, KH Tak, JL Park, JH Kim… - Cancer …, 2023 - Wiley Online Library
Background Early‐onset colorectal cancer (EOCRC) has been increasing in incidence
worldwide but its genomic pathogenesis is mostly undetermined. This study aimed to identify …

The histological and molecular characteristics of early-onset colorectal cancer: a systematic review and meta-analysis

T Lawler, L Parlato, S Warren Andersen - Frontiers in Oncology, 2024 - frontiersin.org
Background: Early-onset colorectal cancer (CRC), defined as diagnosis before age 50, has
increased in recent decades. Although more often diagnosed at advanced stage …

[HTML][HTML] A novel nomogram based on cell cycle-related genes for predicting overall survival in early-onset colorectal cancer

M Xiang, Y Gao, Y Zhou, M Wang, X Yao - BMC cancer, 2023 - Springer
Background Although the incidence of late-onset colorectal cancer (LOCRC) has
decreased, the incidence of early-onset colorectal cancer (EOCRC) is still rising …

[HTML][HTML] Immune microenvironment in sporadic early-onset versus average-onset colorectal cancer

F Andric, A Al-Fairouzi, Y Wettergren, L Szeponik… - Cancers, 2023 - mdpi.com
Simple Summary The incidence of non-hereditary cancer in the left colon and rectum is
increasing in young patients worldwide for unknown reasons. To understand this …

[HTML][HTML] Propolis Has an Anticancer Effect on Early Stage Colorectal Cancer by Affecting Epithelial Differentiation and Gut Immunity in the Tumor Microenvironment

MH Shen, CY Liu, KW Chang, CL Lai, SC Chang… - Nutrients, 2023 - mdpi.com
Colorectal cancer (CRC) is one of the most common cancers and is the second leading
cause of cancer-related death in the world. Due to the westernization of diets, young patients …

[PDF][PDF] The characteristics of head and neck squamous cell cancer in young adults: a retrospective single-center study

M Révész, F Oberna, A Slezák, Ö Ferenczi… - Pathology and …, 2023 - por-journal.com
Head and neck squamous cell carcinoma (HNSCC) was estimated as the sixth most
common cancer with approximately 800,000 new cases yearly worldwide based on the …

Early‐onset colorectal cancer: why it should be high on our list of differentials

C Garrett, D Steffens, M Solomon… - ANZ journal of …, 2022 - Wiley Online Library
Background Early‐onset colorectal cancer (EOCRC)(< 50 years) incidence has increased in
Australia and worldwide. However, the diagnosis of EOCRC is often delayed. Recent …

Differences in Tumor-Associated T cell receptor repertoires between Early-Onset and Average-Onset colorectal cancer

YY Tsai, KG Nair, SV Barot, S Xiang… - JNCI: Journal of the …, 2024 - academic.oup.com
The incidence of colorectal cancer (CRC) among individuals younger than age 50 (early
onset CRC; EOCRC) has substantially increased, yet the etiology and molecular …