In the current century, the development of medicine and molecular biotechnology led to
successful containment and even eradication of some human pathogens, especially in …

During the last forty years we have witnessed impressive advances in the field of antiviral
drug discovery culminating with the introduction of therapies able to stop human …

Viral infections play an important role in human diseases, and recent outbreaks in the
advent of globalization and ease of travel have underscored their prevention as a critical …

Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has been a global public health emergency since …

Abstract Background Influenza viruses (IVs) have become increasingly resistant to antiviral
drugs that target neuraminidase and matrix protein 2 due to gene mutations that alter their …

Influenza is an acute respiratory disease in mammals and domestic poultry that emerges
from zoonotic reservoirs in aquatic birds and bats. Although influenza viruses are among the …

Effective antivirals have been developed against specific viruses, such as HIV, Hepatitis C
virus and influenza virus. This' one bug–one drug'approach to antiviral drug development …

Background We assessed the safety and effectiveness of baloxavir marboxil administration
in Japanese children with influenza. Methods This open-label study administered 1 weight …

Influenza A virus infections in humans generally cause self-limited infections, but can result
in severe disease, secondary bacterial pneumonias, and death. Influenza viruses can …

Influenza viruses cause seasonal epidemics and pandemic outbreaks associated with
significant morbidity and mortality, and a huge cost. Since resistance to the existing anti …