Foam cells: one size doesn't fit all

V Guerrini, ML Gennaro - Trends in immunology, 2019 - cell.com
Chronic inflammation in many infectious and metabolic diseases, and some cancers, is
accompanied by the presence of foam cells. These cells form when the intracellular lipid …

Extracellular vesicles in trypanosomatids: host cell communication

AC Torrecilhas, RP Soares, S Schenkman… - Frontiers in Cellular …, 2020 - frontiersin.org
Trypanosoma cruzi, Trypanosoma brucei and Leishmania (Trypanosomatidae:
Kinetoplastida) are parasitic protozoan causing Chagas disease, African Trypanosomiasis …

Lipid hijacking: a unifying theme in vector-borne diseases

AJ O'Neal, LR Butler, A Rolandelli, SD Gilk, JHF Pedra - Elife, 2020 - elifesciences.org
Vector-borne illnesses comprise a significant portion of human maladies, representing 17%
of global infections. Transmission of vector-borne pathogens to mammals primarily occurs …

Biogenesis and breakdown of lipid droplets in pathological conditions

CM Fader Kaiser, PS Romano, MC Vanrell… - Frontiers in Cell and …, 2022 - frontiersin.org
Lipid droplets (LD) have long been considered as mere fat drops; however, LD have lately
been revealed to be ubiquitous, dynamic and to be present in diverse organelles in which …

Extracellular Vesicles in Trypanosoma cruzi Infection: Immunomodulatory Effects and Future Perspectives as Potential Control Tools against Chagas Disease

N Cortes-Serra, M Gualdron-Lopez… - Journal of …, 2022 - Wiley Online Library
Chagas disease, caused by the protozoa parasite Trypanosoma cruzi, is a neglected
tropical disease and a major public health problem affecting more than 6 million people …

Role of extracellular vesicles in cellular cross talk in malaria

KA Babatunde, B Yesodha Subramanian… - Frontiers in …, 2020 - frontiersin.org
Malaria infection caused by the Plasmodium species is a complex disease in which a fine
balance between host and parasite factors determine the disease severity. While in some …

Guidelines for the purification and characterization of extracellular vesicles of parasites

C Fernandez‐Becerra, P Xander… - Journal of …, 2023 - Wiley Online Library
Parasites are responsible for the most neglected tropical diseases, affecting over a billion
people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible …

A safe ride in extracellular vesicles–small RNA trafficking between plant hosts and pathogens

Q Cai, B He, H Jin - Current Opinion in Plant Biology, 2019 - Elsevier
Highlights•Plant send small RNAs in extracellular vesicles to fungal pathogens.•Cross-
kingdom RNAi is an important regulatory mechanism between plant and eukaryotic …

Extracellular vesicles of Trypanosoma cruzi tissue-culture cell-derived trypomastigotes: Induction of physiological changes in non-parasitized culture cells

L Retana Moreira, F Rodríguez Serrano… - PLoS Neglected …, 2019 - journals.plos.org
Background Trypanosoma cruzi is the obligate intracellular parasite that causes Chagas
disease. The pathogenesis of this disease is a multifactorial complex process that involves a …

Cyclooxygenase (COX)-2 modulates Toxoplasma gondii infection, immune response and lipid droplets formation in human trophoblast cells and villous explants

G de Souza, RJ Silva, ICB Milián, AM Rosini… - Scientific Reports, 2021 - nature.com
Congenital toxoplasmosis is represented by the transplacental passage of Toxoplasma
gondii from the mother to the fetus. Our studies demonstrated that T. gondii developed …