Ovarian cancer encompasses a heterogeneous group of malignancies that involve the
ovaries, fallopian tubes and the peritoneal cavity. Despite major advances made within the …

Objective: We aimed to construct the ferritin autophagy regulatory network and illustrate its
mechanism in ferroptosis, TME immunity and malignant phenotypes of ovarian cancer …

Simple Summary The tumor-surrounding niche comprises not only cancer cells but also
stromal cells, signaling molecules, secreted factors and the extracellular matrix. This niche …

Simple Summary Tumor dormancy is the period during which patients are asymptomatic
before recurrence and it is difficult to target pharmacologically. Inflammatory cytokines …

Previous study revealed that ferritin heavy chain-1 (FTH1) could regulate ferritinophagy and
affect intracellular Fe 2+ content in various tumors, while its N6-methyladenosine (m6A) …

Phospholipase D (PLD) isoenzymes participate in a variety of cellular functions that are
mostly attributed to phosphatidic acid (PA) synthesis. Dysregulation of PLD regulates tumor …

妇科恶性肿瘤严重威胁女性健康. 传统的治疗方案包括手术, 放化疗以及靶向治疗等.
考虑到放化疗可能对非肿瘤部位造成毒性损害, 为了提高治疗效果并减轻不良反应 …

Ovarian cancer is the leading cause of death among all gynecological cancers, with most
patients being diagnosed with metastatic disease. For metastatic implants to form …

Ovarian cancer (OvCa) is one of the leading causes of gynecologic malignancies. Despite
treatment with surgery and chemotherapy, OvCa disseminates and recurs frequently …