Abstract Background in 2010, the European Working Group on Sarcopenia in Older People
(EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying …

Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

The relationship between the age-associated decline in mitochondrial function and its effect
on skeletal muscle physiology and function remain unclear. In the current study, we …

Background Engaging in physical activity (PA) and avoiding sedentary behavior (SB) are
important for healthy ageing with benefits including the mitigation of disability and mortality …

Skeletal muscle is greatly affected by aging, resulting in a loss of metabolic and physical
function. However, the underlying molecular processes and how (lack of) physical activity is …

Living longer is associated with an increased risk of chronic diseases, including impairments
of the musculoskeletal and immune system as well as metabolic disorders and certain …

Background & aims Sarcopenia is a muscle disorder associated with loss of muscle mass,
strength and function. Early screening, diagnosis and treatment may improve outcome in …

Understanding the factors that contribute to exercise response variation is the first step in
achieving the goal of developing personalized exercise prescriptions. This review discusses …

Obesity and aging have both seen dramatic increases in prevalence throughout society.
This review seeks to highlight common pathologies that present with obesity, along with the …

Importance The pathophysiology of exercise intolerance in patients with heart failure with
preserved ejection fraction (HFpEF) remains incompletely understood. Multiple lines of …