Dementia is the seventh leading cause of mortality, and a major source of disability and
dependency in older individuals globally. Cognitive decline (and, to a lesser extent, normal …

A majority of patients with Alzheimer's disease (AD) experience some form of sleep
disruption, including nocturnal sleep fragmentation, increased daytime napping, decreased …

Background: Renin-angiotensin system (RAS) inhibitors have been suggested as protective
agents in Parkinson's disease (PD). However, epidemiological evidence on the association …

Background Prescribing benzodiazepines to older patients is controversial. Anxiety
disorders and benzodiazepines have been associated with dementia, but literature is …

Benzodiazepines (BZDs) and Z-drugs are compounds widely prescribed in medical practice
due to their anxiolytic, hypnotic, and muscle relaxant properties. Yet, their chronic use is …

Sleep is an essential physiological process, especially for proper brain function through the
formation of new pathways and processing information and cognition. Therefore, when …

Despite reducing benzodiazepine prescribing, benzodiazepine‐involving deaths have
substantially increased in Australia. This study aimed to explore patterns in long‐term …

Abstract Background Benzodiazepines (BZDs) and Z-drugs (BZDRs) are among the most
prescribed medications for anxiety and insomnia, especially among older adults. Our …

Background: Benzodiazepines (BZDs) and Non-BZDs (NBZDs) have been widely used for
patients with chronic insomnia. Long-term uses of BZDs may cause cognitive impairment …

Purpose of the review There is strong evidence for a bidirectional association between sleep
disorders and Alzheimer's disease (AD). In particular, insomnia may be a potentially …