[HTML][HTML] GroEL triggers NLRP3 inflammasome activation through the TLR/NF-κB p-p65 axis in human periodontal ligament stem cells: GroEL triggers NLRP3 …
L Zhang, M Duan, X Pu, H Zheng… - Acta Biochimica et …, 2024 - pmc.ncbi.nlm.nih.gov
The interaction between bacteria and the host plays a vital role in the initiation and
progression of systemic diseases, including gastrointestinal and oral diseases, due to the …
progression of systemic diseases, including gastrointestinal and oral diseases, due to the …
The virulence factor GroEL directs the osteogenic and adipogenic differentiation of human periodontal ligament stem cells through the involvement of JNK/MAPK and …
L Zhang, L Cheng, Y Cui, Z Wu, L Cai… - Journal of …, 2021 - Wiley Online Library
Background GroEL, a bacterial metabolite, is an important stimulator of inflammation. The
aim of this study is to confirm the effect of the virulence factor GroEL on differentiation …
aim of this study is to confirm the effect of the virulence factor GroEL on differentiation …
Molecular mechanism of curcumin on periodontitis: a pharmacological network study
JM Guzmán-Flores, CM Arevalo-Caro… - Journal of Oral …, 2023 - Elsevier
Objective This study aimed to identify the molecular mechanism of curcumin on periodontitis
based on a pharmacological network strategy. Methods The potential therapeutic targets of …
based on a pharmacological network strategy. Methods The potential therapeutic targets of …
[HTML][HTML] Alzheimer's Disease and Porphyromonas gingivalis: Exploring the Links
I Shawkatova, V Durmanova, J Javor - Life, 2025 - pmc.ncbi.nlm.nih.gov
Recent research highlights compelling links between oral health, particularly periodontitis,
and systemic diseases, including Alzheimer's disease (AD). Although the biological …
and systemic diseases, including Alzheimer's disease (AD). Although the biological …
Transcriptome and metabolome analysis of osteoblasts identifies disrupted purine metabolism and parathyroid hormone associated pathway induced by P. gingivalis …
D Liu, Y Xiang, M Sun, J Hu, Q Chen, L Liao, Y Liu… - Bone, 2025 - Elsevier
Abstract Porphyromonas gingivalis (P. gingivalis), a major pathogenic bacterium of chronic
periodontitis and central player in the onset and subsequent progression of periodontitis …
periodontitis and central player in the onset and subsequent progression of periodontitis …
The virulence factor GroEL promotes gelatinase secretion from cells in the osteoblast lineage: Implication for direct crosstalk between bacteria and adult cells
L Zhang, Y Cui, Y Yang, J Wei, W Liu, L Cai… - Archives of Oral …, 2021 - Elsevier
Objective The aim of this study was to demonstrate the influence of the virulence factor
GroEL on osteoblast behavior by characterizing the changes of secreted gelatinases …
GroEL on osteoblast behavior by characterizing the changes of secreted gelatinases …