Challenges with assessing and treating pain in research primates: A focused survey and literature review

EA Paterson, PV Turner - Animals, 2022 - mdpi.com
Simple Summary It is crucial that research primates receive adequate pain treatment from
ethical, animal welfare, and research-related perspectives. There is limited research on …

Pharmacokinetics of intravenous, intramuscular, oral, and transdermal administration of flunixin meglumine in pre-wean piglets

HC Kittrell, JP Mochel, JT Brown… - Frontiers in Veterinary …, 2020 - frontiersin.org
Castration and tail-docking of pre-wean piglets are common procedures that are known to
induce pain and would benefit from pain mitigation. Flunixin meglumine (FM) is a non …

Development of a physiologically based pharmacokinetic model for flunixin in cattle and swine following dermal exposure

X Wu, Q Chen, WC Chou, FP Maunsell… - Toxicological …, 2025 - academic.oup.com
Flunixin meglumine is a nonsteroidal anti-inflammatory drug (NSAID). Banamine
Transdermal is a pour-on formulation of flunixin approved for pain control in beef and dairy …

Transdermal flunixin meglumine as a pain relief in donkeys: A pharmacokinetics pilot study

AK McLean, T Falt, EM Abdelfattah, B Middlebrooks… - Metabolites, 2023 - mdpi.com
Recent approval of transdermal flunixin meglumine (FM)(Banamine®) in cattle has opened
the door for the drug's potential application in other species. Transdermal FM could provide …

Pharmacokinetics of transdermal flunixin meglumine and effects on biomarkers of inflammation in horses

HK Knych, RM Arthur, SR Gretler… - Journal of veterinary …, 2021 - Wiley Online Library
Flunixin meglumine is a highly efficacious nonsteroidal anti‐inflammatory drug commonly
used in equine medicine and especially in performance horses. Recently, a new …

A novel transdermal ketoprofen formulation for analgesia in cattle

PC Mills, JG Owens, JB Reinbold… - Journal of Veterinary …, 2022 - Wiley Online Library
Ketoprofen is registered in many countries for injectable administration in cattle. Because it
is soluble in a wide range of excipients, development of a novel transdermal (TD) ketoprofen …

A study to assess the correlation between plasma, oral fluid and urine concentrations of flunixin meglumine with the tissue residue depletion profile in finishing-age …

JL Bates, LA Karriker, SM Rajewski, Z Lin… - BMC veterinary …, 2020 - Springer
Background Flunixin meglumine (FM) was investigated for the effectiveness of plasma, oral
fluid, and urine concentrations to predict tissue residue depletion profiles in finishing-age …

Pharmacokinetics of Transdermal Flunixin Meglumine Following a Single Dose in Marine Toads (Rhinella marina)

G Scott, MM Louis, JA Balko, CM Bublitz… - Veterinary Medicine …, 2020 - Wiley Online Library
Transdermal administration is an important method of pharmacologic drug therapy in
amphibians, made possible by their unique skin physiology and permeability. Despite this …

Non‐Steroidal Anti‐Inflammatory Drugs

C Willette - Pharmacology in Veterinary Anesthesia and …, 2024 - Wiley Online Library
Non‐steroidal anti‐inflammatory drugs (NSAIDs) are a core component of the anti‐
inflammatory and analgesic medicines used in both human and veterinary medicine …

Regulatory and legal considerations of anesthetics and analgesics used in food‐producing animals

T Passler - Farm animal anesthesia: Cattle, small ruminants …, 2022 - Wiley Online Library
Veterinarians and animal owners who are involved in the production of animals for human
consumption are charged with providing healthy, wholesome, and safe products. For food …