The cognitive effect of anticholinergics for patients with overactive bladder

B Welk, K Richardson, JN Panicker - Nature Reviews Urology, 2021 - nature.com
Overactive bladder (OAB) is often treated with medications that block the cholinergic
receptors in the bladder (known as anticholinergics). The effect of this medication class on …

Piezo channels in the urinary system

X Li, J Hu, X Zhao, J Li, Y Chen - Experimental & Molecular Medicine, 2022 - nature.com
The Piezo channel family, including Piezo1 and Piezo2, includes essential
mechanosensitive transduction molecules in mammals. Functioning in the conversion of …

Metabolic syndrome and overactive bladder syndrome may share common pathophysiologies

LN Hsu, JC Hu, PY Chen, WC Lee, YC Chuang - Biomedicines, 2022 - mdpi.com
Metabolic syndrome (MetS) is defined by a group of cardiovascular risk factors, including
impaired glucose tolerance, central obesity, hypertension, and dyslipidemia. Overactive …

[HTML][HTML] Urobiome: An outlook on the metagenome of urological diseases

R Shoemaker, J Kim - Investigative and Clinical Urology, 2021 - ncbi.nlm.nih.gov
The urinary tract likely plays a role in the development of various urinary diseases due to the
recently recognized notion that urine is not sterile. In this mini review, we summarize the …

Overactive bladder: A review and update

I Scarneciu, S Lupu, OG Bratu… - Experimental and …, 2021 - spandidos-publications.com
Overactive bladder syndrome is a chronic, disabling condition with physical, psychological
and social consequences that significantly affects the quality of life of millions of patients …

[HTML][HTML] Native tissue repair of cardinal/uterosacral ligaments cures overactive bladder and prolapse, but only in pre-menopausal women

D Shkarupa, A Zaytseva, N Kubin… - … European Journal of …, 2021 - ncbi.nlm.nih.gov
Results At 3 months, cure rates for frequency, urgency, nocturia and prolapse were
comparable. By the 6-month review, catastrophic failure commenced in the postmenopausal …

Efficacy and safety of mirabegron versus placebo add-on therapy in men with overactive bladder symptoms receiving tamsulosin for underlying benign prostatic …

SA Kaplan, S Herschorn, KT McVary… - The Journal of …, 2020 - auajournals.org
Purpose: PLUS investigated the efficacy and safety of mirabegron add-on therapy in men
with overactive bladder symptoms receiving tamsulosin for underlying lower urinary tract …

Bladder hyperactivity induced by oxidative stress and bladder ischemia: a review of treatment strategies with antioxidants

YH Wu, KS Chueh, SM Chuang, CY Long… - International Journal of …, 2021 - mdpi.com
Overactive bladder (OAB) syndrome, including frequency, urgency, nocturia and urgency
incontinence, has a significantly negative impact on the quality-of-life scale (QoL) and can …

Is coexistent overactive–underactive bladder (with or without detrusor overactivity and underactivity) a real clinical syndrome? ICI‐RS 2019

V Mancini, T Tarcan, M Serati… - Neurourology and …, 2020 - Wiley Online Library
Aims Lower urinary tract symptoms (LUTS) can be classified into symptom syndromes based
on which symptoms are predominant. Overactive bladder (OAB) syndrome, a storage …

[HTML][HTML] Drugs currently undergoing preclinical or clinical trials for the treatment of overactive bladder: a review

S Joseph, SA Maria, J Peedicayil - Current Therapeutic Research, 2022 - Elsevier
Background Overactive bladder (OAB) is a common clinical condition for which current drug
treatment comprises drugs blocking the cholinergic nerve supply, or augmenting the …