Spinal cord injury (SCI) is a devastating neurological disorder that affects thousands of
individuals each year. Over the past decades an enormous progress has been made in our …

Virtually all phases of spinal cord injury pathogenesis, including inflammation, cell
proliferation and differentiation, as well as tissue remodeling, are mediated in part by …

Traumatic spinal cord injury (SCI) triggers a neuro-inflammatory response dominated by
tissue-resident microglia and monocyte derived macrophages (MDMs). Since activated …

Aim Spinal cord injury (SCI) involves multiple pathological processes. Ferroptosis has been
shown to play a critical role in the injury process. We wanted to explore whether zinc can …

The role of microglia in spinal cord injury (SCI) remains poorly understood and is often
confused with the response of macrophages. Here, we use specific transgenic mouse lines …

Spinal cord injury (SCI) creates an inflammatory microenvironment characterized by
damage-associated molecular patterns (DAMPs) and immune cell activation that exacerbate …

Stem cell-derived exosomes have recently been regarded as potential drugs for treating
spinal cord injury (SCI) by reducing reactive oxygen species (ROS) and suppressing M1 …

INTRODUCTION The capacity of a tissue to regenerate itself rests on the potential of its
resident cells to replace cells lost to injury. Some tissues, such as skin or intestine, do this …

Tissue repair after spinal cord injury requires the mobilization of immune and glial cells to
form a protective barrier that seals the wound and facilitates debris clearing, inflammatory …

Neuropsychological deficits, including impairments in learning and memory, occur after
spinal cord injury (SCI). In experimental SCI models, we and others have reported that such …