Cell surface proteoglycans are known to be important regulators of many aspects of cell
behavior. The principal family of transmembrane proteoglycans is the syndecans, of which …

Abstract Interleukin 6 (IL-6), a pleiotropic inflammatory cytokine, is produced transiently due
to tissue damage and infections. Nonetheless, IL-6 contributes to the host regenerative …

Recent preclinical and clinical observations have offered relevant insights on the
etiopathogenesis of late onset Alzheimer′ s disease (AD) and upregulated …

Despite the arrival of novel therapies, multiple myeloma (MM) remains incurable and new
treatment options are needed. Chimeric antigen receptor (CAR) T cells are genetically …

B-cell maturation antigen (BCMA) is a highly plasma cell-selective protein expressed on
malignant plasma cells of patients with multiple myeloma (MM), and it is a defined …

Discoid Lupus Erythematosus (DLE) is a chronic cutaneous disease of unknown etiology
and of immunoinflammatory origin that is characterized by inflammatory plaques and may …

Tumor necrosis factor (TNF) superfamily consists of 19 ligands and 29 receptors and is
related to multiple cellular events from proliferation and differentiation to apoptosis and …

Multiple myeloma (MM) remains an incurable plasma cells malignancy because of its
complex genetic heterogeneity and high relapse rate post immunotherapy. The encouraging …

The interaction between leukocytes and cytokine-activated retinal endothelium is an
initiating step in non-infectious uveitis involving the posterior eye, mediated by cell adhesion …

Multiple myeloma (MM) is a tumor type characterized by the unregulated proliferation of
clonal plasma cells in the bone marrow. Immunotherapy based on chimeric antigen receptor …