The recent dramatic rise in obesity rates is an alarming global health trend that consumes an
ever increasing portion of health care budgets in Western countries. The root cause of …

During the 1990s, transmembranal proteins in the central nervous system (CNS) that
recognize the principal compound of marijuana, the delta-9-tetrahydrocannabinol (Δ9-THC) …

BACKGROUND: The endocannabinoid system is a possible target in the treatment of eating
disorders. We used positron emission tomography to investigate the type 1 cannabinoid …

Phthalates, used as plasticizers, have become a ubiquitous contaminant and have been
reported for their potential to induce toxicity in living organisms. Among them, di-isononyl …

Marijuana use activates cannabinoid receptors (CB‐Rs) producing several behavioral
effects related to addiction, mood, and appetite. We investigated the association between …

In obesity, a dysregulation of the endocannabinoid system has been shown. The
endocannabinoid receptor blockage by rimonabant demonstrated interesting metabolic …

Obesity and binge eating disorder are detrimental health conditions that are associated with
lower qualities of life. Individuals with obesity often face societal discrimination and …

The endocannabinoid system comprises amides, esters and ethers of long chain
polyunsaturated fatty acids. Narachidonoylethanolamide (anandamide; ANA) and 2 …

Endogenous cannabinoid signaling, mediated predominately by CB1 receptor activation, is
involved in food intake control and body weight regulation. Despite advances in determining …

Purpose Several lines of evidence strongly implicate a dysfunctional endocannabinoid
system (ECS) in eating disorders. Using [18 F] MK-9470 and small animal positron emission …