Baseline expression of exosomal miR-92a-3p and miR-221-3p could predict the response to first-line chemotherapy and survival in metastatic colorectal cancer

A Gherman, L Balacescu, C Popa, C Cainap… - International Journal of …, 2023 - mdpi.com
The status of predictive biomarkers in metastatic colorectal cancer is currently
underdeveloped. Our study aimed to investigate the predictive value of six circulating …

Tumor stem cell-derived exosomal microRNA-17-5p inhibits anti-tumor immunity in colorectal cancer via targeting SPOP and overexpressing PD-L1

W Sun, J Cui, Y Ge, J Wang, Y Yu, B Han, B Liu - Cell Death Discovery, 2022 - nature.com
Exosomes are known to transmit microRNAs (miRNAs) to affect human cancer progression,
and miR-17-5p has been manifested to exert facilitated effects on colorectal cancer (CRC) …

Serum small RNAs in metastatic colorectal cancer predict response to chemotherapy and characterize high-risk patients

R Mjelle, AK Kristensen, TS Solheim, GS Westvik… - Molecular Cancer, 2024 - Springer
Metastatic colorectal cancer (mCRC) presents significant challenges in clinical management
due to its heterogeneity and variable response to treatment. In this study, we conducted …

Long non‐coding RNA TMPO‐AS1 facilitates the progression of colorectal cancer cells via sponging miR‐98‐5p to upregulate BCAT1 expression

J Ye, Y Yan, L Xin, J Liu, T Tang… - … of Gastroenterology and …, 2022 - Wiley Online Library
Abstract Background and Aim Colorectal cancer, as a common malignant carcinoma in the
gastrointestinal tract, has a high mortality globally. However, the specific molecular …

miR-485-3p and miR-4728-5p as tumor suppressors in pathogenesis of colorectal cancer

T Gurer, A Aytekin, E Caki, S Gezici - Molecular Biology, 2022 - Springer
MicroRNAs (miRNAs) are a class of small noncoding RNAs that have major functions in the
development and progression of colorectal cancer (CRC) as tumor suppressors or …

Role of different types of RNA molecules in the severity prediction of SARS-CoV-2 patients

P Jeyananthan - Pathology-Research and Practice, 2023 - Elsevier
SARS-CoV-2 pandemic is the current threat of the world with enormous number of
deceases. As most of the countries have constraints on resources, particularly for intensive …

A comprehensive framework for analysis of microRNA sequencing data in metastatic colorectal cancer

E Høye, B Fromm, PHM Böttger, D Domanska… - NAR …, 2022 - academic.oup.com
Although microRNAs (miRNAs) contribute to all hallmarks of cancer, miRNA dysregulation in
metastasis remains poorly understood. The aim of this work was to reliably identify miRNAs …

[Retracted] Ferulic Acid Protects Endothelial Cells from Hypoxia‐Induced Injury by Regulating MicroRNA‐92a

Y Huang, L Tian, Y Liu, J Liu… - Applied Bionics and …, 2022 - Wiley Online Library
Background & Aim. Ferulic acid (FA), the main effective ingredient in Angelica sinensis, has
been widely recognized as the cause of angiogenesis and proliferation of human umbilical …

An independent validation study of candidate microRNAs as predictive biomarkers for bevacizumab-based therapy in patients with metastatic colorectal cancer

D Kiss, T Machackova, K Souckova, P Fabian… - in vivo, 2021 - iv.iiarjournals.org
Background/Aim: The monoclonal antibody bevacizumab is a standard drug used in
combination with oxaliplatin (FOLFOX) or irinotecan (FOLFIRI) based chemotherapy in the …

[PDF][PDF] Identifying Candidate Biomarkers of Clinical Response to Ustekinumab in Psoriasis

S Solanky - 2024 - kclpure.kcl.ac.uk
The development and use of biologic drugs, including ustekinumab, secukinumab,
adalimumab and newer anti-interleukin (IL)-23p19 biologics, have revolutionised treatment …