Urocortins (Ucns), peptides belonging to the corticotropin-releasing hormone (CRH) family,
are classified into Ucn1, Ucn2, and Ucn3. They are involved in regulating several body …

Malignant tumors express multiple factors that have some role in the regulating networks
supporting their ectopic growth. Recently, increased interest has been developing in the …

Abstract Fibronectin 1 (FN1) is a glycoprotein that is involved in cell adhesion and migration
processes including embryogenesis, wound healing, blood coagulation, host defenses and …

BACKGROUND & AIMS: The corticotrophin-releasing hormone (CRH) family of peptides
modulates intestinal inflammation and the CRH receptor 2 (CRHR2) suppresses postnatal …

Methods mRNA expression of CRH-family members was analyzed in CRC (N= 56) and
control (N= 46) samples, 7 CRC cell lines and normal NCM460 cells. Immunohistochemical …

Background Caveolae play a significant role in disease phenotypes such as cancer,
diabetes, bladder dysfunction, and muscular dystrophy. The aim of this study was to …

Prostate cancer (PRAD) is a common and fatal malignancy. It is difficult to manage clinically
due to drug resistance and poor prognosis, thus creating an urgent need for novel …

Simple Summary Prostate cancer (PC) is the second most common cancer worldwide and
steroid hormone plays an important role in prostate carcinogenesis. Most patients with PC …

Colonic epithelium is the first line of defense against various pathological offenses in the gut.
Previous studies have shown that the peptides of the corticotropin-releasing hormone (CRH) …

Abstract Urocortin (Ucn), a corticotropin-releasing factor (CRF)-related neuropeptide binding
both CRF type 1 receptor (CRFR1) and CRFR2, has recently been found in prostate cancer …