The vitamin D receptor (VDR) belongs to the nuclear receptor superfamily of transcription
factors. The VDR is expressed in diverse brain regions and has been implicated in the …

The blood–brain barrier (BBB) regulates the delivery of oxygen and important nutrients to
the brain through active and passive transport and prevents neurotoxins from entering the …

The integrity of blood–brain‐barrier (BBB) is essential for normal brain functions, synaptic
remodeling, and angiogenesis. BBB disruption is a common pathology during Parkinson's …

Neurodegenerative diseases, featured by progressive loss of structure or function of
neurons, are considered incurable at present. Movement disorders like tremor and postural …

Nuclear receptors, also known as ligand-activated transcription factors, regulate gene
expression upon ligand signals and present as attractive therapeutic targets especially in …

There is increasing evidence for blood–brain barrier (BBB) alterations in Parkinson's
disease (PD), the second most common neurodegenerative disorder with rapidly rising …

Drug transporters play an important role in the maintenance of chemical balance and
homeostasis in different tissues. In addition to their physiological functions, they are crucial …

A metabolic illness known as non-alcoholic fatty liver disease (NAFLD), affects more than
one-quarter of the world's population. Bile acids (BAs), as detergents involved in lipid …

The blood–brain barrier (BBB) expresses a high abundance of transporters, particularly P‐
glycoprotein (P‐gp), that regulate endogenous and exogenous molecule uptake and …

ATP-binding cassette (ABC) transporters are one of the largest groups of transporter families
in humans. ABC transporters mediate the translocation of a diverse range of substrates …