Relatively little is known about the neuropathophysiology of binge-eating disorder (BED).
Here, the evidence from neuroimaging, neurocognitive, genetics, and animal studies are …

This review summarizes evidence of dysregulated reward circuitry function in a range of
neurodevelopmental and psychiatric disorders and genetic syndromes. First, the …

Importance Binge-eating disorder (BED), a public health problem associated with
psychopathological symptoms and obesity and possibly with metabolic syndrome, lacks …

Anorexia nervosa (AN) is a severe psychiatric disorder associated with food avoidance and
malnutrition. In this study, we wanted to test whether we would find brain reward alterations …

Objective: This review attempted to examine the validity and clinical utility of the DSM‐IV
binge eating disorder (BED) diagnosis across a wide range of validating strategies. Method …

Abstract Second-generation antipsychotics (SGAs), such as risperidone, clozapine and
olanzapine, are the most common drug treatments for schizophrenia. SGAs presented an …

BACKGROUND: An important step in obesity research involves identifying neurobiological
underpinnings of nonfood reward processing unique to specific subgroups of obese …

Objective: To examine the literature on binge eating to gain a better understanding of its
biological foundations and their role in eating disorders. Method: Literature review and …

Central dopaminergic mechanisms are involved in the motivational aspects of eating and
food choices. This review focuses on human and animal data investigating the importance of …

Developed countries around the world are experiencing an epidemic of overeating and
obesity with significant costs at a personal, familial, and societal level. While most research …