Carcinoma of the lungs is among the most menacing forms of malignancy and has a poor
prognosis, with a low overall survival rate due to delayed detection and ineffectiveness of …

Chitosan (CS), the second most plentiful natural polysaccharide next to cellulose, has
valuable characteristics including biocompatibility, nontoxicity and biodegradability. CS is …

Highlights•Clearance routes of nanoparticles in the lung are presented.•Factors influencing
nanoparticle transaction are discussed.•Physicochemical properties of the nanoparticles …

Pulmonary administration route has been extensively exploited for the treatment of local
lung diseases such as asthma, chronic obstructive pulmonary diseases and respiratory …

Oral inhalation is the preferred route for delivery of small molecules to the lungs, because
high tissue levels can be achieved shortly after application. Biologics are mainly …

Breast cancer is considered one of the utmost neoplastic diseases globally, with a high
death rate of patients. Over the last decades, many approaches have been studied to early …

Adagen, an enzyme replacement treatment for adenosine deaminase deficiency, was the
first protein-polymer conjugate to be approved in early 1990 s. Post this regulatory approval …

Malaria is a vector-and blood-borne infection that is responsible for a large number of
deaths around the world. Most of the currently used antimalarial therapeutics suffer from …

Inhalation therapy has been reported as the most effective treatment for respiratory bacterial
infections due to the increasing relevance of drug bioavailability. Drug delivery systems …

Cancer is a chronic disease that is responsible for the high death rate, globally. The
administration of anticancer drugs is one crucial approach that is employed for the treatment …