Advances in drug delivery technology for the treatment of glioblastoma multiforme

GD Cha, T Kang, S Baik, D Kim, SH Choi… - Journal of Controlled …, 2020 - Elsevier
Glioblastoma multiforme (GBM) is a particularly aggressive and malignant type of brain
tumor, notorious for its high recurrence rate and low survival rate. The treatment of GBM is …

Cancer metastases: early dissemination and late recurrences

S Friberg, A Nystrom - Cancer growth and metastasis, 2015 - journals.sagepub.com
Background Metastatic cells from a primary tumor can occur before the primary cancer is
detected. Metastatic cells can also remain in the patient for many years after removal of the …

Intrinsic gene expression profiles of gliomas are a better predictor of survival than histology

LAM Gravendeel, MCM Kouwenhoven, O Gevaert… - Cancer research, 2009 - AACR
Gliomas are the most common primary brain tumors with heterogeneous morphology and
variable prognosis. Treatment decisions in patients rely mainly on histologic classification …

Surgical resection of malignant gliomas—role in optimizing patient outcome

IY Eyüpoglu, M Buchfelder, NE Savaskan - Nature Reviews Neurology, 2013 - nature.com
Malignant gliomas represent one of the most devastating human diseases. Primary
treatment of these tumours involves surgery to achieve tumour debulking, followed by a …

Multiple high-grade gliomas: epidemiology, management, and outcome. A systematic review and meta-analysis

DT Di Carlo, F Cagnazzo, N Benedetto, R Morganti… - Neurosurgical …, 2019 - Springer
Multiple high-grade gliomas (M-HGGs) are well--separated tumors, differentiated as
multifocal (MF) and multicentric (MC) by their MRI features. The authors performed a …

Prognostic significance of c‐Met expression in glioblastomas

DS Kong, SY Song, DH Kim, KM Joo, JS Yoo, JS Koh… - Cancer, 2009 - Wiley Online Library
BACKGROUD: The authors investigated whether expression of c‐Met protein in
glioblastomas is associated with overall survival and biologic features representing tumor …

Prognosis of patients with multifocal glioblastoma: a case-control study

CG Patil, A Yi, A Elramsisy, J Hu, D Mukherjee… - Journal of …, 2012 - thejns.org
Object The prognosis of patients with glioblastoma who present with multifocal disease is
not well documented. The objective of this study was to determine whether multifocal …

Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma

Q Liu, Y Liu, W Li, X Wang, R Sawaya, FF Lang… - Acta …, 2015 - Springer
Ten to twenty percent of newly diagnosed glioblastoma (GBM) patients initially present with
multiple lesions, termed multifocal or multicentric GBM (M-GBM). The prognosis of these …

[HTML][HTML] Biological effect of an alternating electric field on cell proliferation and synergistic antimitotic effect in combination with ionizing radiation

EH Kim, YJ Kim, HS Song, YK Jeong, JY Lee, J Sung… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Alternating electric fields at an intermediate frequency (100~ 300 kHz), referred to as tumour-
treating fields (TTF), are believed to interrupt the process of mitosis via apoptosis and to act …

Cerebral blood volume measurements by perfusion-weighted MR imaging in gliomas: ready for prime time in predicting short-term outcome and recurrent disease?

S Bisdas, M Kirkpatrick, P Giglio… - American Journal …, 2009 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Current classification and grading of primary brain tumors
has significant limitations. Our aim was to determine whether the relative cerebral volume …