Pectin is a heterogeneous hydrocolloid present in the primary cell wall and middle lamella in
all dicotyledonous plants, more commonly in the outer fruit coat or peel as compared to the …

Disruption of the native membrane organization of Ras by the farnesyltransferase inhibitor
tipifarnib in the late 1990s constituted the first indirect approach to drug target Ras. Since …

Introduction Natural killer (NK) cells and natural killer T (NKT) cells are implicated in the
development and progression of colorectal cancer (CRC). Tumor cells express NK cell …

Immunotherapy with checkpoint inhibitors (ICIs) has radically changed the landscape of
therapeutic opportunities in oncology, but much still needs to be understood from a …

ABSTRACT Galectin-3 (Gal-3) is a multifunctional protein that plays a pivotal role in the
initiation and progression of various central nervous system diseases, including cancer …

Glioblastoma has remained the deadliest primary brain tumor while its current therapy offers
only modest survival prolongation. Immunotherapy has failed to record notable benefits in …

Purpose Overexpression of galectin-3, a β-galactoside-binding lectin, is associated with
fibrotic diseases and cancer. Selvigaltin is an oral galectin-3 inhibitor, previously …

Galectins, the glycan-binding family of lectins, have been known to mediate a multitude of
biological functions with the help of their unique 'sugar-sensing'carbohydrate recognition …

Malignant brain tumors constitute a disaster in the lives of patients, either in the form of
extremely low survival in glioblastoma, or the serious long-term adverse effects of therapy in …

: Introduction: Ameloblastoma is a benign odontogenic neoplasm with a high risk of
recurrence. Ameloblastoma stromal fibroblasts are associated with tumor growth and …