COVID-19 mortality is strongly associated with the development of severe pneumonia and
acute respiratory distress syndrome with the worst outcome resulting in cytokine release …

Brain pericytes are perivascular cells that regulate capillary function, and this localization
puts them in a pivotal position for the regulation of central nervous system (CNS) …

The notion of “immune privilege” of the brain has been revised to accommodate its
infiltration, at steady state, by immune cells that participate in normal neurophysiology …

As the biomedical community produces datasets that are increasingly complex and high
dimensional, there is a need for more sophisticated computational tools to extract biological …

Esophageal squamous-cell carcinoma (ESCC), one of the most prevalent and lethal
malignant disease, has a complex but unknown tumor ecosystem. Here, we investigate the …

SARS-CoV-2 infection has recently been declared a pandemic. Some patients showing
severe symptoms exhibit drastic inflammation and airway damage. In this study, we re …

Sweet's syndrome, also known as Acute Febrile Neutrophilic Dermatosis, is a rare
inflammatory condition. It is considered to be the prototype disease of neutrophilic …

Pericytes (PC) are mural cells that surround endothelial cells in small blood vessels. PC
have traditionally been credited with structural functions, being essential for vessel …

Background Pericytes are multipotent cells present in every vascularized tissue in the body.
Despite the fact that they are well-known for more than a century, pericytes are still …

Mucosally active subunit vaccines are an unmet clinical need due to lack of licensed
immunostimulants suitable for vaccine antigens. Here, we show that intranasal …