Classic models for dynamic contrast‐enhanced MRI
SP Sourbron, DL Buckley - NMR in Biomedicine, 2013 - Wiley Online Library
Dynamic contrast‐enhanced MRI (DCE‐MRI) is a functional MRI method where T1‐
weighted MR images are acquired dynamically after bolus injection of a contrast agent. The …
weighted MR images are acquired dynamically after bolus injection of a contrast agent. The …
Perfusion magnetic resonance imaging: a comprehensive update on principles and techniques
GH Jahng, KL Li, L Ostergaard… - Korean journal of …, 2014 - synapse.koreamed.org
Perfusion is a fundamental biological function that refers to the delivery of oxygen and
nutrients to tissue by means of blood flow. Perfusion MRI is sensitive to microvasculature …
nutrients to tissue by means of blood flow. Perfusion MRI is sensitive to microvasculature …
Blood-brain barrier leakage in patients with early Alzheimer disease
HJ Van De Haar, S Burgmans, JFA Jansen… - Radiology, 2016 - pubs.rsna.org
Purpose To investigate whether the blood-brain barrier (BBB) leaks blood-circulating
substances in patients with early forms of Alzheimer disease (AD), and if so, to examine the …
substances in patients with early forms of Alzheimer disease (AD), and if so, to examine the …
Radiomic profiling of glioblastoma: identifying an imaging predictor of patient survival with improved performance over established clinical and radiologic risk models
Purpose To evaluate whether radiomic feature–based magnetic resonance (MR) imaging
signatures allow prediction of survival and stratification of patients with newly diagnosed …
signatures allow prediction of survival and stratification of patients with newly diagnosed …
APOE4 accelerates advanced-stage vascular and neurodegenerative disorder in old Alzheimer's mice via cyclophilin A independently of amyloid-β
A Montagne, AM Nikolakopoulou, MT Huuskonen… - Nature Aging, 2021 - nature.com
Abstract Apolipoprotein E4 (APOE4), the main susceptibility gene for Alzheimer's disease
(AD), leads to vascular dysfunction, amyloid-β pathology, neurodegeneration and dementia …
(AD), leads to vascular dysfunction, amyloid-β pathology, neurodegeneration and dementia …
Prediction of tissue outcome and assessment of treatment effect in acute ischemic stroke using deep learning
Background and Purpose—Treatment options for patients with acute ischemic stroke
depend on the volume of salvageable tissue. This volume assessment is currently based on …
depend on the volume of salvageable tissue. This volume assessment is currently based on …
IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human …
The recent identification of IDH mutations in gliomas and several other cancers suggests
that this pathway is involved in oncogenesis; however effector functions are complex and yet …
that this pathway is involved in oncogenesis; however effector functions are complex and yet …
Blood-brain barrier impairment and hypoperfusion are linked in cerebral small vessel disease
Objective To investigate the link between blood-brain-barrier (BBB) permeability and
cerebral blood flow (CBF) and the relation with white matter hyperintensities (WMH) in …
cerebral blood flow (CBF) and the relation with white matter hyperintensities (WMH) in …
Remote ischemic perconditioning as an adjunct therapy to thrombolysis in patients with acute ischemic stroke: a randomized trial
KD Hougaard, N Hjort, D Zeidler, L Sørensen… - Stroke, 2014 - Am Heart Assoc
Background and Purpose—Remote ischemic preconditioning is neuroprotective in models
of acute cerebral ischemia. We tested the effect of prehospital rPerC as an adjunct to …
of acute cerebral ischemia. We tested the effect of prehospital rPerC as an adjunct to …
Real‐time diffusion‐perfusion mismatch analysis in acute stroke
Diffusion‐perfusion mismatch can be used to identify acute stroke patients that could benefit
from reperfusion therapies. Early assessment of the mismatch facilitates necessary …
from reperfusion therapies. Early assessment of the mismatch facilitates necessary …