In the United States, 36.5% of women between the ages of 20 and 39 years are obese. This
obesity results in not only metabolic disorders including type II diabetes and cardiovascular …

Ovarian aging is a natural and physiological aging process characterized by loss of quantity
and quality of oocyte or follicular pool. As it is generally accepted that women are born with a …

Highlights What are the main findings? For the first time, microplastics were detected and
localized by electron microscopy in human placentas. The presence of microplastics was …

BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …

Molecular mimicry has been proposed as a cause of the autoimmune phenomena observed
in COVID-19 [1–4], the syndrome associated with the infection by severe acute respiratory …

Endometriosis an important cause of female infertility and seriously impact physical and
psychological health of patients. Endometriosis is now considered to be a public health …

Development of the early embryo takes place under low oxygen tension. Under such
conditions, the embryo implants and the trophectoderm, the outer layer of blastocyst …

Mammalian oocytes and early embryos derived from in vitro production are highly
susceptible to a variety of cellular stresses. During oocyte maturation and preimplantation …

Endoplasmic reticulum (ER) and lysosomes coordinate a network of key cellular processes
including unfolded protein response (UPR) and autophagy in response to stress. How ER …

Preeclampsia is one of the most common obstetrical complications worldwide. The
pathomechanism of this disease begins with abnormal placentation in early pregnancy …