Biological functions of lymphatic vessels

TV Petrova, GY Koh - Science, 2020 - science.org
BACKGROUND Blood and lymphatic vessel networks form two arms of the vertebrate
cardiovascular system that play complementary roles in body homeostasis maintenance and …

The Importance of Mechanical Forces for in vitro Endothelial Cell Biology

E Gordon, L Schimmel, M Frye - Frontiers in Physiology, 2020 - frontiersin.org
Blood and lymphatic vessels are lined by endothelial cells which constantly interact with
their luminal and abluminal extracellular environments. These interactions confer physical …

Lymphatic vessels in bone support regeneration after injury

L Biswas, J Chen, J De Angelis, A Singh… - Cell, 2023 - cell.com
Blood and lymphatic vessels form a versatile transport network and provide inductive signals
to regulate tissue-specific functions. Blood vessels in bone regulate osteogenesis and …

Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid

JH Ahn, H Cho, JH Kim, SH Kim, JS Ham, I Park… - Nature, 2019 - nature.com
Recent work has shown that meningeal lymphatic vessels (mLVs), mainly in the dorsal part
of the skull, are involved in the clearance of cerebrospinal fluid (CSF), but the precise route …

Exosomal long noncoding RNA LNMAT2 promotes lymphatic metastasis in bladder cancer

C Chen, Y Luo, W He, Y Zhao, Y Kong… - The Journal of …, 2020 - Am Soc Clin Investig
Patients with bladder cancer (BCa) with clinical lymph node (LN) metastasis have an
extremely poor prognosis. VEGF-C has been demonstrated to play vital roles in LN …

Harnessing matrix stiffness to engineer a bone marrow niche for hematopoietic stem cell rejuvenation

X Zhang, D Cao, L Xu, Y Xu, Z Gao, Y Pan, M Jiang… - Cell stem cell, 2023 - cell.com
Hematopoietic stem cell (HSC) self-renewal and aging are tightly regulated by paracrine
factors from the bone marrow niche. However, whether HSC rejuvenation could be achieved …

Lymphatic vessel: origin, heterogeneity, biological functions, and therapeutic targets

Z Hu, X Zhao, Z Wu, B Qu, M Yuan, Y Xing… - … and Targeted Therapy, 2024 - nature.com
Lymphatic vessels, comprising the secondary circulatory system in human body, play a
multifaceted role in maintaining homeostasis among various tissues and organs. They are …

VE-cadherin is required for lymphatic valve formation and maintenance

Y Yang, B Cha, ZY Motawe, RS Srinivasan, JP Scallan - Cell reports, 2019 - cell.com
The lymphatic vasculature requires intraluminal valves to maintain forward lymph flow.
Lymphatic valves form and are constantly maintained by oscillatory fluid flow throughout life …

[HTML][HTML] Squishy matters–Corneal mechanobiology in health and disease

SM Thomasy, BC Leonard, MA Greiner… - Progress in retinal and …, 2024 - Elsevier
The cornea, as a dynamic and responsive tissue, constantly interacts with mechanical forces
in order to maintain its structural integrity, barrier function, transparency and refractive …

The role of YAP and TAZ in angiogenesis and vascular mimicry

T Azad, M Ghahremani, X Yang - Cells, 2019 - mdpi.com
Angiogenesis, the formation of new blood vessels from pre-existing vasculature, is a
physiological process that begins in utero and continues throughout life in both good health …