In consequence of their biological effects, conformationally constrained carbocyclic β-amino
acids have generated great interest among synthetic and medicinal chemists in the past 2 …

Side chain-fluorinated amino acids are useful tools in medicinal chemistry and protein
science. In this review, we outline some general strategies for incorporating fluorine atom (s) …

Peptide-based drug research has received high attention in the field of medicinal chemistry
over the past decade. For drug design, to improve proteolytic stability, it is desirable to …

The area of fluorinated amino acid synthesis has seen rapid growth over the past decade.
As reports of singly fluorinated natural amino acid derivatives have grown, researchers have …

The selective introduction of fluorine onto the skeleton of an aminocyclopentane or
cyclohexane carboxylate has been developed through a novel and efficient fluoride opening …

Nucleophilic fluorination is one of the fundamental reactions in organic chemistry, as well as
a convenient tool for the synthesis of fluorinated building blocks with a potential biological …

Fluorine‐containing organic molecules have generated increasing impact in drug research
over the past decade. Their preparation and development of novel synthetic methods …

Kinetic and sequential kinetic enzymatic routes for the synthesis of enantiomeric β-and γ-
amino acids through enzymatic ring cleavage of the corresponding lactams in organic …

A metal-promoted degradation of 2-azetidinones to afford CC′ N-pincer ligands is reported.
The hexahydride complex OsH6 (P i Pr3) 2 (1) reacts with (±)-cis-1-(4-methoxyphenyl)-3 …

The current Account gives an insight into the synthesis of some N-heterocyclic β-amino acid
derivatives and various functionalized saturated azaheterocycles accessed from substituted …