Modelling autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) using mice and zebrafish

G Dougnon, H Matsui - International journal of molecular sciences, 2022 - mdpi.com
Autism spectrum disorders (ASD) and attention-deficit/hyperactivity disorder (ADHD) are two
debilitating neurodevelopmental disorders. The former is associated with social impairments …

Exploring potential impacts of pregnancy-related maternal immune activation and extracellular vesicles on immune alterations observed in autism spectrum disorder

V de Lima Kaminski, RT Michita, JH Ellwanger, TD Veit… - Heliyon, 2023 - cell.com
Abstract Autism Spectrum Disorder (ASD) is a set of neurodevelopmental disorders usually
observed in early life, with impacts on behavioral and social skills. Incidence of ASD has …

[HTML][HTML] Behavioral and neurochemical profile of MK-801 adult zebrafish model: Forebrain β2-adrenoceptors contribute to social withdrawal and anxiety-like behavior

P Perdikaris, CR Dermon - Progress in Neuro-Psychopharmacology and …, 2022 - Elsevier
Deficits in social communication and interaction are core clinical symptoms characterizing
multiple neuropsychiatric conditions, including autism spectrum disorder (ASD) and …

Cellular and molecular mechanisms underlying glioblastoma and zebrafish models for the discovery of new treatments

P Reimunde, A Pensado-López, M Carreira Crende… - Cancers, 2021 - mdpi.com
Simple Summary Glioblastoma (GBM) is one of the greatest challenges facing neuro-
oncology today. Current treatments are far from satisfactory and, given the poor prognosis of …

Molecular dysregulation in autism spectrum disorder

PS Gill, JL Clothier, A Veerapandiyan… - Journal of Personalized …, 2021 - mdpi.com
Autism Spectrum Disorder (ASD) comprises a heterogeneous group of neurodevelopmental
disorders with a strong heritable genetic component. At present, ASD is diagnosed solely by …

[HTML][HTML] Decoding the genetic landscape of autism: A comprehensive review

M Al-Beltagi, NK Saeed, AS Bediwy… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Autism spectrum disorder (ASD) is a complex neurodevelopmental
condition characterized by heterogeneous symptoms and genetic underpinnings. Recent …

Autism spectrum disorder genes: disease-related networks and compensatory strategies

HK Lim, JH Yoon, M Song - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
The mammalian brain comprises structurally and functionally distinct regions. Each of these
regions has characteristic molecular mechanisms that mediate higher-order tasks, such as …

Dysfunction of Prkcaa links social behavior defects with disturbed circadian rhythm in zebrafish

H Hu, Y Long, G Song, S Chen, Z Xu, Q Li… - International Journal of …, 2023 - mdpi.com
Protein kinase Cα (PKCα/PRKCA) is a crucial regulator of circadian rhythm and is
associated with human mental illnesses such as autism spectrum disorders and …

Using Human‐Induced Pluripotent Stem Cell Derived Neurons on Microelectrode Arrays to Model Neurological Disease: A Review

S Lv, E He, J Luo, Y Liu, W Liang, S Xu… - Advanced …, 2023 - Wiley Online Library
In situ physiological signals of in vitro neural disease models are essential for studying
pathogenesis and drug screening. Currently, an increasing number of in vitro neural disease …

Comparative evaluation of different chemical agents induced Autism Spectrum Disorder in experimental Wistar rats

AR Sharma, G Batra, N Dhir, A Jain, T Modi… - Behavioural Brain …, 2024 - Elsevier
Abstract Autism Spectrum Disorder (ASD) is a complex neurodevelopmental condition with
uncertain etiology and pathophysiology. Several studies revealed that the commonly used …