The importance of the tumor microenvironment in the therapeutic management of cancer
C Pottier, A Wheatherspoon, P Roncarati… - Expert review of …, 2015 - Taylor & Francis
Tumor prognosis is generally defined by various tumor parameters. However, it is well
known that paracrine, endocrine and cell–cell interactions between the tumor and its …
known that paracrine, endocrine and cell–cell interactions between the tumor and its …
Inflammatory breast cancer promotes development of M2 tumor-associated macrophages and cancer mesenchymal cells through a complex chemokine network
A Valeta-Magara, A Gadi, V Volta, B Walters, R Arju… - Cancer research, 2019 - AACR
Inflammatory breast cancer (IBC) is a highly aggressive form of breast cancer that displays
profound cancer stem cell (CSC) and mesenchymal features that promote rapid metastasis …
profound cancer stem cell (CSC) and mesenchymal features that promote rapid metastasis …
Cytokines secreted by macrophages isolated from tumor microenvironment of inflammatory breast cancer patients possess chemotactic properties
Although there is a growing literature describing the role of macrophages in breast cancer,
the role of macrophages in inflammatory breast cancer (IBC) is unclear. The aim of present …
the role of macrophages in inflammatory breast cancer (IBC) is unclear. The aim of present …
Tumor microenvironmental plasmacytoid dendritic cells contribute to breast cancer lymph node metastasis via CXCR4/SDF-1 axis
R Gadalla, H Hassan, SA Ibrahim, MS Abdullah… - Breast cancer research …, 2019 - Springer
Abstract Purpose Plasmacytoid dendritic cells (PDCs) infiltration into breast cancer tissues is
associated with poor prognosis. Also, CXCR4 shows compelling evidences to be exploited …
associated with poor prognosis. Also, CXCR4 shows compelling evidences to be exploited …
[HTML][HTML] IL-8 secreted by tumor associated macrophages contribute to lapatinib resistance in HER2-positive locally advanced breast cancer via activation of Src/STAT3 …
S Ahmed, HT Mohamed, N El-Husseiny… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Locally advanced breast cancer (LABC) is an aggressive disease characterized by late
clinical presentation, large tumor size, treatment resistance and low survival rate. Expression …
clinical presentation, large tumor size, treatment resistance and low survival rate. Expression …
Leptin is overexpressed in the tumor microenvironment of obese patients with estrogen receptor positive breast cancer
The present study aimed to investigate the potential role of leptin in the progression of breast
cancer and the associated cell proliferation signalling pathway (s). A total of 44 female …
cancer and the associated cell proliferation signalling pathway (s). A total of 44 female …
Progress for immunotherapy in inflammatory breast cancer and emerging barriers to therapeutic efficacy
Simple Summary Despite recent advances in the treatment of other breast cancer subtypes,
inflammatory breast cancer (IBC) remains a significant clinical challenge, with an overall 5 …
inflammatory breast cancer (IBC) remains a significant clinical challenge, with an overall 5 …
Prognostic impact of perioperative lymphocyte–monocyte ratio in patients with bladder cancer undergoing radical cystectomy
T Yoshida, H Kinoshita, K Yoshida, T Mishima… - Tumor Biology, 2016 - Springer
Various systemic inflammatory response biomarkers are associated with oncological
outcome. We evaluated the superiority of prognostic predictive accuracy between neutrophil …
outcome. We evaluated the superiority of prognostic predictive accuracy between neutrophil …
The immunomodulatory role of tumor Syndecan-1 (CD138) on ex vivo tumor microenvironmental CD4+ T cell polarization in inflammatory and non-inflammatory …
Herein, we aimed to identify the immunomodulatory role of tumor Syndecan-1 (CD138) in
the polarization of CD4+ T helper (Th) subsets isolated from the tumor microenvironment of …
the polarization of CD4+ T helper (Th) subsets isolated from the tumor microenvironment of …
Inflammatory Breast Cancer: The Secretome of HCMV+ Tumor-Associated Macrophages Enhances Proliferation, Invasion, Colony Formation, and Expression of …
Inflammatory breast cancer (IBC) is a highly aggressive phenotype of breast cancer that is
characterized by a high incidence early metastasis. We previously reported a significant …
characterized by a high incidence early metastasis. We previously reported a significant …