Making and shaping endochondral and intramembranous bones

GL Galea, MR Zein, S Allen… - Developmental …, 2021 - Wiley Online Library
Skeletal elements have a diverse range of shapes and sizes specialized to their various
roles including protecting internal organs, locomotion, feeding, hearing, and vocalization …

The spine: a strong, stable, and flexible structure with biomimetics potential

F Galbusera, T Bassani - Biomimetics, 2019 - mdpi.com
From its first appearance in early vertebrates, the spine evolved the function of protecting the
spinal cord, avoiding excessive straining during body motion. Its stiffness and strength …

The developmental impacts of natural selection on human pelvic morphology

M Young, D Richard, M Grabowski, BM Auerbach… - Science …, 2022 - science.org
Evolutionary responses to selection for bipedalism and childbirth have shaped the human
pelvis, a structure that differs substantially from that in apes. Morphology related to these …

Integrated multi-omics analysis of PBX1 in mouse adult neural stem-and progenitor cells identifies a transcriptional module that functionally links PBX1 to TCF3/4

V Laub, E Nan, L Elias, IJ Donaldson… - Nucleic Acids …, 2024 - academic.oup.com
Developmental transcription factors act in networks, but how these networks achieve cell-
and tissue specificity is still poorly understood. Here, we explored pre-B cell leukemia …

'Building a perfect body': control of vertebrate organogenesis by PBX-dependent regulatory networks

L Selleri, V Zappavigna, E Ferretti - Genes & development, 2019 - genesdev.cshlp.org
Pbx genes encode transcription factors that belong to the TALE (three-amino-acid loop
extension) superclass of homeodomain proteins. We have witnessed a surge in information …

Transcription factors of the Alx family: Evolutionarily conserved regulators of deuterostome skeletogenesis

JM Khor, CA Ettensohn - Frontiers in genetics, 2020 - frontiersin.org
Members of the alx gene family encode transcription factors that contain a highly conserved
Paired-class, DNA-binding homeodomain, and a C-terminal OAR/Aristaless domain …

The multifactor pelvis: An alternative to the adaptationist approach of the obstetrical dilemma

A Warrener - Evolutionary Anthropology: Issues, News, and …, 2023 - Wiley Online Library
The obstetrical dilemma describes the competing demands that a bipedally adapted pelvis
and a large‐brained neonate place on human childbirth and is the predominant model …

Sexual dimorphism and allometry in human scapula shape

ECS Lee, RL Lawrence, MJ Rainbow - Journal of Anatomy, 2024 - Wiley Online Library
Scapula shape is highly variable across humans and appears to be sexually dimorphic—
differing significantly between biological males and females. However, previous …

[HTML][HTML] Advances in skeletal genomics research across tissues and cells

G Housman - Current Opinion in Genetics & Development, 2024 - Elsevier
Phenotypic variation within the skeleton has biological, behavioral, and biomedical
functional implications for individuals and species. Thus, it is critical to understand how …

Morphology, evolution, and the whole organism imperative: Why evolutionary questions need multi‐trait evolutionary quantitative genetics

BM Auerbach, KRR Savell… - American Journal of …, 2023 - Wiley Online Library
Abstract Since Washburn's New Physical Anthropology, researchers have sought to
understand the complexities of morphological evolution among anatomical regions in …