Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic
lysis, resulting in cytomembrane rupture and release of immunostimulatory components …

Zinc metabolism at the cellular level is critical for many biological processes in the body. A
key observation is the disruption of cellular homeostasis, often coinciding with disease …

This review explores the pivotal role of the nucleotide-binding oligomerization domain
(NOD)-like receptor protein 3 (NLRP3) inflammasome in the pathogenesis of diabetes and …

Complex multicellular organisms are composed of distinct tissues involving specialized cells
that can perform specific functions, making such life forms possible. Species are defined by …

Behçet disease (BD) and relapsing polychondritis (RP) are chronic multisystem disorders
characterized by recurrent flare-ups of tissue inflammation. Major clinical manifestations of …

Inflammasome activation drives pyroptotic cell death and the release of inflammatory
cytokines, and many diseases involve its overactivation. Zinc is essential for all organisms …

The impact of the microbiota residing in the body on local and systemic immune responses
has been increasingly recognized. The major gut microbe metabolites' short-chain fatty …

Zinc homeostasis plays an essential role in maintaining immune function and is tightly
regulated by zinc transporters. We previously reported that the zinc transporter SLC39A10 …

Anastomotic leakage (AL) is a defect of the intestinal wall at the anastomotic site and is one
of the most severe complications in colorectal surgery. Previous studies have shown that the …

Zinc, a crucial trace element is vital for the growth and development of humans. It is
frequently described as 'the flower of life'and 'the source of intelligence'. Zinc supplements …