α1‐, α2‐ and β‐adrenoceptors in the urinary bladder, urethra and prostate

MC Michel, W Vrydag - British journal of pharmacology, 2006 - Wiley Online Library
We have systematically reviewed the presence, functional responses and regulation of α1‐,
α2‐and β‐adrenoceptors in the bladder, urethra and prostate, with special emphasis on …

Cardiac alpha1-adrenergic receptors: novel aspects of expression, signaling mechanisms, physiologic function, and clinical importance

TD O'Connell, BC Jensen, AJ Baker, PC Simpson… - Pharmacological …, 2014 - Elsevier
Adrenergic receptors (AR) are G-protein-coupled receptors (GPCRs) that have a crucial role
in cardiac physiology in health and disease. Alpha 1-ARs signal through Gα q, and signaling …

Alpha-adrenoceptor subtypes

BC Calzada, AA de Artiñano - Pharmacological research, 2001 - Elsevier
Different studies have led to our present knowledge of the membrane receptors responsible
for mediating the responses to the endogenous catecholamines. These receptors were …

α1-Adrenergic Receptor Subtypes: Molecular Structure, Function, and Signaling

RM Graham, DM Perez, J Hwa, MT Piascik - Circulation research, 1996 - Am Heart Assoc
The a, ARs are important mediators of sympathetic nervous system responses, particularly
those involved in cardiovascular homeostasis, such as arteriolar smooth muscle constriction …

Distribution of α1a-, α1b-and α1d-adrenergic receptor mRNA in the rat brain and spinal cord

HEW Day, S Campeau, SJ Watson Jr, H Akil - Journal of chemical …, 1997 - Elsevier
The technique of in situ hybridization with specific ribonucleotide probes was used to
determine the distribution patterns of mRNA encoding the α1a-, α1b-and α1d-adrenoceptor …

α1-Adrenoceptor subtypes

H Zhong, KP Minneman - European journal of pharmacology, 1999 - Elsevier
α1-Adrenoceptors are one of three subfamilies of receptors (α1, α2, β) mediating responses
to adrenaline and noradrenaline. Three α1-adrenoceptor subtypes are known (α1A, α1B …

Interleukin-1 beta induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in culture.

JN Palmer, WE Hartogensis, M Patten… - The Journal of …, 1995 - Am Soc Clin Investig
Interleukin-1 (IL-1), initially called" endogenous pyrogen," is primarily known as a mediator
of inflammation. However, it also plays many other diverse physiologic roles including the …

Knockout of the α1A/C-adrenergic receptor subtype: the α1A/C is expressed in resistance arteries and is required to maintain arterial blood pressure

DG Rokosh, PC Simpson - Proceedings of the National …, 2002 - National Acad Sciences
α1-adrenergic receptors (ARs) play a major role in blood pressure regulation. The three α1-
AR subtypes (A/C, B, and D) stimulate contraction of isolated arteries, but it is uncertain how …

Classification of α1-adrenoceptor subtypes

MC Michel, B Kenny, DA Schwinn - Naunyn-Schmiedeberg's archives of …, 1995 - Springer
Two α 1-adrenoceptor subtypes (α 1A and α 1B) have been detected in various tissues by
pharmacological techniques, and three distinct cDNAs encoding α 1-adrenoceptor subtypes …

Alpha-1–adrenergic receptors in heart failure: The adaptive arm of the cardiac response to chronic catecholamine stimulation

BC Jensen, TD O'Connell… - Journal of cardiovascular …, 2014 - journals.lww.com
Alpha-1–adrenergic receptors (ARs) are G protein–coupled receptors activated by
catecholamines. The alpha-1A and alpha-1B subtypes are expressed in mouse and human …