Reagent‐and metal‐free anodic C− C cross‐coupling of aniline derivatives

L Schulz, M Enders, B Elsler… - Angewandte Chemie …, 2017 - Wiley Online Library
The dehydrogenative cross‐coupling of aniline derivatives to 2, 2′‐diaminobiaryls is
reported. The oxidation is carried out electrochemically, which avoids the use of metals and …

A Mini-Review: Intermolecular interactions of small molecules containing amide groups-based organic semiconductors and their applications

CK Trinh, NI Abdo - Journal of Molecular Structure, 2022 - Elsevier
Research about small molecules-based optoelectronic devices revealed the way to improve
the device performance by increasing the conjugation length in organic semiconductors to …

Beyond organic solvents: synthesis of a 5-HT 4 receptor agonist in water

JD Bailey, E Helbling, A Mankar, M Stirling, F Hicks… - Green …, 2021 - pubs.rsc.org
Reducing or eliminating organic solvent use in pharmaceutical manufacturing is perhaps the
most effective way to reduce the environmental, health, and safety impacts of drug …

A new silica-supported organocatalyst based on L-proline: An efficient heterogeneous catalyst for one-pot synthesis of spiroindolones in water

A Khalafi-Nezhad, ES Shahidzadeh, S Sarikhani… - Journal of Molecular …, 2013 - Elsevier
A simple and practical synthetic strategy for the synthesis of a novel silica-supported
organocatalyst system based on L-proline (SSLP) has been developed. First, silica was …

A simple and eco-sustainable method for the O-Boc protection/deprotection of various phenolic structures under water-mediated/catalyst-free conditions

Z Cheraiet, S Hessainia, S Ouarna… - … Chemistry Letters and …, 2013 - Taylor & Francis
A greener, efficient, and chemoselective protocol for O-Boc protection/deprotection of a wide
range of phenol derivatives is reported under catalyst-free conditions in water-related …

Reagens‐und metallfreie anodische C‐C‐Kreuzkupplung von Anilinderivaten

L Schulz, M Enders, B Elsler, D Schollmeyer… - Angewandte …, 2017 - Wiley Online Library
Vorgestellt wird die oxidative Kreuzkupplung von Anilinderivaten zu 2, 2′‐Diaminobiarylen.
Der Oxidationsschritt wird elektrochemisch durchgeführt, ohne die Notwendigkeit von …

Fluorous-assisted chemoenzymatic synthesis of heparan sulfate oligosaccharides

C Cai, DM Dickinson, L Li, S Masuko, M Suflita… - Organic …, 2014 - ACS Publications
The chemoenzymatic synthesis of heparan sulfate tetrasaccharide (1) and hexasaccharide
(2) with a fluorous tag attached at the reducing end is reported. The fluorous tert-butyl …

Deprotection of N-Boc Groups under Continuous-Flow High-Temperature Conditions

B Li, R Li, P Dorff, JC McWilliams… - The Journal of …, 2019 - ACS Publications
The scope of thermolytic, N-Boc deprotection was studied on 26 compounds from the Pfizer
compound library, representing a diverse set of structural moieties. Among these …

A Brønsted Acidic Deep Eutectic Solvent for N-Boc Deprotection

D Procopio, C Siciliano, R De Rose, S Trombino… - Catalysts, 2022 - mdpi.com
The tert-butyloxycarbonyl (Boc) group is one of the most widely used amine-protecting
groups in multistep reactions in synthetic organic chemistry as well as in peptide synthesis …

A sustainable, efficient, and potentially cost-effective approach to the antimalarial drug candidate MMV688533

RD Kavthe, KS Iyer, JC Caravez, BH Lipshutz - Chemical science, 2023 - pubs.rsc.org
A 6-step synthesis of the antimalarial drug candidate MMV688533 is reported. Key
transformations carried out under aqueous micellar conditions include two Sonogashira …