Remodeling of T cell dynamics during long COVID is dependent on severity of SARS-CoV-2 infection

M Wiech, P Chroscicki, J Swatler, D Stepnik… - Frontiers in …, 2022 - frontiersin.org
Several COVID-19 convalescents suffer from the post-acute COVID-syndrome (PACS)/long
COVID, with symptoms that include fatigue, dyspnea, pulmonary fibrosis, cognitive …

Comprehensive antibody and cytokine profiling in hospitalized COVID-19 patients in relation to clinical outcomes in a large Belgian cohort

P Ruytinx, P Vandormael, J Fraussen, Z Pieters… - Scientific Reports, 2023 - nature.com
The immune response in patients with Coronavirus Disease 2019 (COVID-19) is highly
variable and is linked to disease severity and mortality. However, antibody and cytokine …

Spleen tyrosine kinase inhibition restores myeloid homeostasis in COVID-19

G Wigerblad, SA Warner, MJ Ramos-Benitez… - Science …, 2023 - science.org
Spleen tyrosine kinase (SYK) is a previously unidentified therapeutic target that inhibits
neutrophil and macrophage activation in coronavirus disease 2019 (COVID-19) …

The pathophysiology of postacute sequelae of COVID-19 (PASC): Possible role for persistent inflammation

GD Marshall Jr - Asia Pacific Allergy, 2023 - journals.lww.com
Background: As the SARS-CoV-2-induced pandemic wanes, a substantial number of
patients with acute Corona Virus-induced disease (COVID-19 continue to have symptoms …

Longitudinal transcriptomic analysis reveals persistent enrichment of iron homeostasis and erythrocyte function pathways in severe COVID-19 ARDS

M Eltobgy, F Johns, D Farkas, L Leuenberger… - Frontiers in …, 2024 - frontiersin.org
Introduction The acute respiratory distress syndrome (ARDS) is a common complication of
severe COVID-19 and contributes to patient morbidity and mortality. ARDS is a …

Risk of death in comorbidity subgroups of hospitalized COVID-19 patients inferred by routine laboratory markers of systemic inflammation on admission: a …

R Cocoş, B Mahler, A Turcu-Stiolica, A Stoichiță… - Viruses, 2022 - mdpi.com
Our study objective was to construct models using 20 routine laboratory parameters on
admission to predict disease severity and mortality risk in a group of 254 hospitalized COVID …

Serological study of CoronaVac vaccine and booster doses in Chile: immunogenicity and persistence of anti-SARS-CoV-2 spike antibodies

L Vargas, N Valdivieso, F Tempio, V Simon, D Sauma… - BMC medicine, 2022 - Springer
Background Chile was severely affected by COVID19 outbreaks but was also one of the first
countries to start a nationwide program to vaccinate against the disease. Furthermore, Chile …

COVID-19 associated with cryptococcosis: a scoping review

A Quincho-Lopez, N Poma… - Therapeutic …, 2024 - journals.sagepub.com
Background: There is growing evidence of fungal infections associated with COVID-19. The
development of cryptococcosis in these patients has been infrequently reported. However, it …

T cell immune response predicts survival in severely ill COVID-19 patients requiring venovenous extracorporeal membrane oxygenation support

Z Ulakcsai, L Szabo, Z Szabo, E Karaszi… - Frontiers in …, 2023 - frontiersin.org
Introduction There is a critical gap in understanding which SARS-CoV-2 patients would
benefit most from venovenous extracorporeal membrane oxygenation (VV-ECMO) support …

Severely ill and high-risk COVID-19 patients exhibit increased peripheral circulation of CD62L+ and perforin+ T cells

KE Lesteberg, P Araya, KA Waugh, L Chauhan… - Frontiers in …, 2023 - frontiersin.org
Introduction The emergence of SARS-CoV-2, which causes COVID-19, has led to over 400
million reported cases worldwide. COVID-19 disease ranges from asymptomatic infection to …