Breast cancer is the most common invasive malignancy in the world, with millions of
survivors living today. Type 2 diabetes mellitus (T2DM) is also a globally prevalent disease …

Cardiac fibrosis is a common pathological change associated with cardiac injuries and
diseases. Even though the accumulation of collagens and other extracellular matrix (ECM) …

Activated beige adipocytes have therapeutic potential due to their ability to improve glucose
and lipid homeostasis. To date, the origin of beige adipocytes remains enigmatic. Whether …

Hair follicles (HFs) function as hubs for stem cells, immune cells, and commensal microbes,
which must be tightly regulated during homeostasis and transient inflammation. Here we …

Active thermogenesis in the brown adipose tissue (BAT) facilitating the utilization of lipids
and glucose is critical for maintaining body temperature and reducing metabolic diseases …

Background During muscle regeneration, excessive formation of adipogenic and fibrogenic
tissues, from their respective fibro/adipogenic progenitors (FAPs), impairs functional …

The present narrative review gathers the studies reported so far, addressing sex differences
in the effects of cold exposure, feeding pattern and age on brown adipose tissue (BAT) …

Obesity is currently affecting more than 40% of the Americans, and if it progresses with this
rate, soon one out of two Americans will be obese. Obesity is an important risk factor for …

Objective Understanding the signaling mechanisms that control brown adipose tissue (BAT)
development is relevant to understanding energy homeostasis and obesity. The AKT …

Tissue engineered vascular grafts hold promise for the creation of functional blood vessels
from biodegradable scaffolds. Because the precise mechanisms regulating this process are …