Elevated blood purine levels as a biomarker of seizures and epilepsy
Objective There is a major unmet need for a molecular biomarker of seizures or epilepsy that
lends itself to fast, affordable detection in an easy‐to‐use point‐of‐care device. Purines such …
lends itself to fast, affordable detection in an easy‐to‐use point‐of‐care device. Purines such …
Electrochemical platform for the detection of adenosine using a sandwich-structured molecularly imprinted polymer-based sensor
An innovative sandwich MIP-based electrochemical sensor was fabricated for the fast and
selective detection of adenosine. The covalent-imprinted biomimetic recognition element …
selective detection of adenosine. The covalent-imprinted biomimetic recognition element …
A 3D-printed, multi-modal microfluidic device for measuring nitric oxide and ATP release from flowing red blood cells
In this paper, a 3D-printed multi-modal device was designed and fabricated to
simultaneously detect nitric oxide (NO) and adenosine triphosphate (ATP) in red blood cell …
simultaneously detect nitric oxide (NO) and adenosine triphosphate (ATP) in red blood cell …
Validation of a LC/MSMS method for simultaneous quantification of 9 nucleotides in biological matrices
M Cortese, C Delporte, D Dufour, C Noyon… - Talanta, 2019 - Elsevier
Nucleotides play a role in inflammation processes: cAMP and cGMP in the endothelial
barrier function, ADP in platelet aggregation, ATP and UTP in vasodilatation and/or …
barrier function, ADP in platelet aggregation, ATP and UTP in vasodilatation and/or …
A LC-MS/MS method for quantifying adenosine, guanosine and inosine nucleotides in human cells
LC Jimmerson, LR Bushman, ML Ray… - Pharmaceutical …, 2017 - Springer
Purpose To develop and validate a method for the simultaneous measurement of
adenosine, guanosine, and inosine derived from mono (MP) and triphosphate (TP) forms in …
adenosine, guanosine, and inosine derived from mono (MP) and triphosphate (TP) forms in …
Impaired antioxidant capacity causes a disruption of metabolic homeostasis in sickle erythrocytes
NA Chaves, TGP Alegria, LS Dantas, LES Netto… - Free Radical Biology …, 2019 - Elsevier
This study examined particularly relevant redox pathways such as glycolysis, pentose
phosphate pathway (PPP), metHb reductase and nucleotide metabolism, in order to better …
phosphate pathway (PPP), metHb reductase and nucleotide metabolism, in order to better …
[HTML][HTML] Advancements in Adenine Nucleotides Extraction and Quantification from a Single Drop of Human Blood
Adenine nucleotides (ANs)—adenosine 5′-triphosphate (ATP), adenosine 5′-
diphosphate (ADP), and adenosine 5′-monophosphate (AMP)—are essential for energy …
diphosphate (ADP), and adenosine 5′-monophosphate (AMP)—are essential for energy …
[HTML][HTML] Development and validation of LC-MS/MS method for quantification of ATP, ADP and AMP in dried blood spot, liver and brain of neonate mice pups
The objective of this study was to develop and validate a method using liquid
chromatography coupled with a mass spectrometer (LC–MS/MS) for simultaneous analysis …
chromatography coupled with a mass spectrometer (LC–MS/MS) for simultaneous analysis …
Effects of a Leucaena leucocephala leaf extract on xanthine oxidase activity and serum oxypurine levels in mice
F Martinez-Morales, JR Zapata-Morales… - Biotecnia, 2024 - scielo.org.mx
There is a need for novel alternatives to the medical use of allopurinol. In this sense, the
present study obtained a leaf extract from L. leucocephala, and its chemical composition …
present study obtained a leaf extract from L. leucocephala, and its chemical composition …
Measurement of levofloxacin in human plasma samples for a reliable and accessible drug monitoring
OH Aragon-Martinez, MA Isiordia-Espinoza… - Clinical …, 2017 - Elsevier
Objectives Levofloxacin monitoring is recommended to obtain clinical cure and low
incidence of antimicrobial resistance. During the monitoring procedure, levofloxacin should …
incidence of antimicrobial resistance. During the monitoring procedure, levofloxacin should …