Polyphenols as caloric-restriction mimetics and autophagy inducers in aging research

A Yessenkyzy, T Saliev, M Zhanaliyeva, AR Masoud… - Nutrients, 2020 - mdpi.com
It has been thought that caloric restriction favors longevity and healthy aging where
autophagy plays a vital role. However, autophagy decreases during aging and that can lead …

Role (s) of cytokines in pulpitis: latest evidence and therapeutic approaches

MMY Khorasani, G Hassanshahi, A Brodzikowska… - Cytokine, 2020 - Elsevier
Pulpitis is known as a typical inflammation of dental pulp tissue, and microorganisms of the
oral microbiome are involved in this opportunistic infection. Studies indicated that several …

Punicalagin prevents inflammation in LPS-induced RAW264. 7 macrophages by inhibiting FoxO3a/autophagy signaling pathway

Y Cao, J Chen, G Ren, Y Zhang, X Tan, L Yang - Nutrients, 2019 - mdpi.com
Punicalagin, a hydrolysable tannin of pomegranate juice, exhibits multiple biological effects,
including inhibiting production of pro-inflammatory cytokines in macrophages. Autophagy …

[HTML][HTML] Autophagy, a double-edged sword for oral tissue regeneration

X Xu, J Wang, Y Xia, Y Yin, T Zhu, F Chen… - Journal of Advanced …, 2024 - Elsevier
Background Oral health is of fundamental importance to maintain systemic health in
humans. Stem cell-based oral tissue regeneration is a promising strategy to achieve the …

Polyphenols in dental applications

N Kharouf, Y Haikel, V Ball - Bioengineering, 2020 - mdpi.com
(1) Background: polyphenols are a broad class of molecules extracted from plants and have
a large repertoire of biological activities. Biomimetic inspiration from the effects of tea or red …

Natural compounds and mesenchymal stem cells: implications for inflammatory-impaired tissue regeneration

W Li, Z Xiang, W Yu, X Huang, Q Jiang… - Stem Cell Research & …, 2024 - Springer
Inflammation is a common and important pathological process occurring in any part of the
body and relating to a variety of diseases. Effective tissue repair is critical for the survival of …

JNK signaling as a key modulator of soft connective tissue physiology, pathology, and healing

G Nikoloudaki, S Brooks, AP Peidl, D Tinney… - International journal of …, 2020 - mdpi.com
In healthy individuals, the healing of soft tissues such as skin after pathological insult or post
injury follows a relatively predictable and defined series of cell and molecular processes to …

Lipopolysaccharide downregulates the osteo-/odontogenic differentiation of stem cells from apical papilla by inducing autophagy

S Lei, XM Liu, Y Liu, J Bi, S Zhu, X Chen - Journal of Endodontics, 2020 - Elsevier
Introduction The dentinogenesis potential of stem cells during dentin-pulp tissue
regeneration may be compromised by microorganism components. Here we aimed to …

The application of resveratrol to mesenchymal stromal cell-based regenerative medicine

C Hu, L Li - Stem cell research & therapy, 2019 - Springer
Currently, the transplantation of mesenchymal stromal cells (MSCs) has emerged as an
effective strategy to protect against tissue and organ injury. MSC transplantation also serves …

Healthy benefits and edible delivery systems of resveratrol: a review

Z Xie, X Chen - Food Reviews International, 2023 - Taylor & Francis
Resveratrol, as a promising bioactive, has received significant attention in the food industry
owing to its multiple health-benefits. The increasing studies on resveratrol encapsulation to …