Despite its complexity, blood is probably the best understood developmental system, largely
due to seminal experimentation in the mouse. Clinically, hematopoietic stem cell (HSC) …

''It seems more than ever likely that blood-derived stem tive capacity. 47-49 In the allogeneic
setting, mobilized blood cells have also been used instead of BM. 50 Umbilical cord cells …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Bone marrow transplantation is the primary therapy for numerous hematopoietic disorders.
The efficiency of bone marrow transplantation depends on the function of long-term …

Reactive oxygen species (ROS) play an important role in determining the fate of normal
stem cells. Low levels of ROS are required for stem cells to maintain quiescence and self …

AC133 is one of a new panel of murine hybridoma lines producing monoclonal IgG
antibodies (mAbs) to a novel stem cell glycoprotein antigen with a molecular weight of 120 …

The increased use of Peripheral Blood Stem Cells (PBSC) to reconstitute hematopoiesis in
autotransplant and, more recently, allotransplant settings has not been associated with a …

Mouse hematopoiesis is initiated by long-term hematopoietic stem cells (HSC) that
differentiate into a series of multipotent progenitors that exhibit progressively diminished self …

Genome editing with targeted nucleases and DNA donor templates homologous to the
break site has proven challenging in human hematopoietic stem and progenitor cells …

The early stages of lymphoid cell formation were studied by testing the differentiative
potential of phenotypically defined subsets of CD34+ bone marrow cells. A subpopulation of …