The “Polyploid Hop”: shifting challenges and opportunities over the evolutionary lifespan of genome duplications

P Baduel, S Bray, M Vallejo-Marin, F Kolář… - Frontiers in Ecology and …, 2018 - frontiersin.org
The duplication of an entire genome is no small affair. Whole genome duplication (WGD) is
a dramatic mutation with long-lasting effects, yet it occurs repeatedly in all eukaryotic …

Towards a unified understanding of lithium action in basic biology and its significance for applied biology

E Jakobsson, O Argüello-Miranda, SW Chiu… - The Journal of …, 2017 - Springer
Lithium has literally been everywhere forever, since it is one of the three elements created in
the Big Bang. Lithium concentration in rocks, soil, and fresh water is highly variable from …

Genome evolution across 1,011 Saccharomyces cerevisiae isolates

J Peter, M De Chiara, A Friedrich, JX Yue, D Pflieger… - Nature, 2018 - nature.com
Large-scale population genomic surveys are essential to explore the phenotypic diversity of
natural populations. Here we report the whole-genome sequencing and phenotyping of …

Polyploidy, the nucleotype, and novelty: the impact of genome doubling on the biology of the cell

JJ Doyle, JE Coate - International Journal of Plant Sciences, 2019 - journals.uchicago.edu
Polyploidy is a key mechanism of genome evolution and speciation, particularly in plants.
Many aspects of polyploidy have been elucidated with the tools that have become available …

Polyploidy can drive rapid adaptation in yeast

AM Selmecki, YE Maruvka, PA Richmond, M Guillet… - Nature, 2015 - nature.com
Polyploidy is observed across the tree of life, yet its influence on evolution remains
incompletely understood,,,. Polyploidy, usually whole-genome duplication, is proposed to …

Diploid-dominant life cycles characterize the early evolution of Fungi

KR Amses, DR Simmons… - Proceedings of the …, 2022 - National Acad Sciences
Most of the described species in kingdom Fungi are contained in two phyla, the Ascomycota
and the Basidiomycota (subkingdom Dikarya). As a result, our understanding of the biology …

Development of a comprehensive genotype-to-fitness map of adaptation-driving mutations in yeast

S Venkataram, B Dunn, Y Li, A Agarwala, J Chang… - Cell, 2016 - cell.com
Adaptive evolution plays a large role in generating the phenotypic diversity observed in
nature, yet current methods are impractical for characterizing the molecular basis and fitness …

Adaptation to high ethanol reveals complex evolutionary pathways

K Voordeckers, J Kominek, A Das… - PLoS …, 2015 - journals.plos.org
Tolerance to high levels of ethanol is an ecologically and industrially relevant phenotype of
microbes, but the molecular mechanisms underlying this complex trait remain largely …

[HTML][HTML] Origins of eukaryotic sexual reproduction

U Goodenough, J Heitman - Cold Spring Harbor …, 2014 - cshperspectives.cshlp.org
Sexual reproduction is a nearly universal feature of eukaryotic organisms. Given its ubiquity
and shared core features, sex is thought to have arisen once in the last common ancestor to …

Whole Genome Analysis of 132 Clinical Saccharomyces cerevisiae Strains Reveals Extensive Ploidy Variation

YO Zhu, G Sherlock, DA Petrov - G3: Genes, Genomes …, 2016 - academic.oup.com
Budding yeast has undergone several independent transitions from commercial to clinical
lifestyles. The frequency of such transitions suggests that clinical yeast strains are derived …