Benzimidazole–Oxadiazole Hybrids—Development in Medicinal Chemistry: An Overview

RM Bhat, V Hegde, S Budagumpi… - Chemical Biology & …, 2024 - Wiley Online Library
To increase the success rate of drug discovery, one practical strategy is to begin molecular
hybridisation. The presence of two or more pharmacophores in a single unit leads to a …

Design, Synthesis, Molecular Modeling and Biological Evaluation of Novel Pyrazole Benzimidazolone Derivatives as Potent Antioxidants

M Adardour, M Ait Lahcen, M Oubahmane, W Ettahiri… - Pharmaceuticals, 2023 - mdpi.com
In the present study, we used benzimidazolone as a starting material to efficiently synthesize
several hybrid compounds of pyrazole benzimidazolone derivatives by the 1, 3-dipolar …

Design, Synthesis, DFT, docking Studies, and antimicrobial evaluation of novel benzimidazole containing sulphonamide derivatives

K Singh, VK Singh, R Mishra, A Sharma, A Pandey… - Bioorganic …, 2024 - Elsevier
In silico approaches have been employed to design a new series of benzimidazole-
containing sulphonamide derivatives and qualified compounds have been synthesized to …