Triazoles are important five-membered heterocyclic scaffold due to their extensive biological
activities. This framework can be readily obtained in good to excellent yields on the …

Imidazole ring is an important five‐membered aromatic heterocycle widely present in natural
products and synthetic molecules. The unique structural feature of imidazole ring with …

A visible-light photoredox-catalyzed method is reported that enables the coupling between
benzylic C–H substrates and N–H azoles. Classically, medicinally relevant N-benzyl azoles …

Triazole compounds containing three nitrogen atoms in the five-membered aromatic azole
ring are readily able to bind with a variety of enzymes and receptors in biological system via …

Breast cancer, a most common malignancy in women, was known to be associated with
steroid hormone estrogen. The discovery of estrogen receptor (ER) gave us not only a …

Postmenopausal women are at high risk of developing breast cancer due to estrogen
production in peripheral tissues of the body other than ovaries. Aromatase is present in …

Aromatase, a cytochrome P450 enzyme complex present in breast tissues, plays a
significant role in the biosynthesis of important endogenous estrogens from androgens. The …

Ba'zinc'ga! A zinc‐catalyzed sequence involving a cyclization with a subsequent C O, C
N, or C C bond formation enables the preparation of a variety of valuable furfuryl ethers …

A mild and efficient DBN-mediated addition reaction of α-(trifluoromethyl) styrenes with
diazoles, triazoles, tetrazoles, and primary, secondary, and secondary cyclic amines was …

Thymidine phosphorylase (TP) is over expressed in several solid tumors and its inhibition
can offer unique target suitable for drug discovery in cancer. A series of 1, 2, 4-triazoles 3a …