Structural basis for vascular endothelial growth factor receptor activation and implications for disease therapy

F Shaik, GA Cuthbert, S Homer-Vanniasinkam… - Biomolecules, 2020 - mdpi.com
Vascular endothelial growth factors (VEGFs) bind to membrane receptors on a wide variety
of cells to regulate diverse biological responses. The VEGF-A family member promotes …

Vascular endothelial growth factor ligands and receptors in breast cancer

KK Brogowska, M Zajkowska, B Mroczko - Journal of Clinical Medicine, 2023 - mdpi.com
Breast cancer (BC) is the most common malignancy responsible for the largest number of
deaths in women worldwide. The risk of developing BC is predisposed by many factors such …

MALAT1-dependent hsa_circ_0076611 regulates translation rate in triple-negative breast cancer

C Turco, G Esposito, A Iaiza, F Goeman… - Communications …, 2022 - nature.com
Abstract Vascular Endothelial Growth Factor A (VEGFA) is the most commonly expressed
angiogenic growth factor in solid tumors and is generated as multiple isoforms through …

Vagus nerve stimulation optimized cardiomyocyte phenotype, sarcomere organization and energy metabolism in infarcted heart through FoxO3A-VEGF signaling

B Luo, Y Wu, S Liu, X Li, H Zhu, L Zhang, F Zheng… - Cell death & …, 2020 - nature.com
Vagus nerve stimulation (VNS) restores autonomic balance, suppresses inflammation action
and minimizes cardiomyocyte injury. However, little knowledge is known about the VNS'role …

Transamniotic stem cell therapy for experimental congenital diaphragmatic hernia: structural, transcriptional, and cell kinetics analyses in the nitrofen model

AV Chalphin, SP Lazow, DF Labuz, SA Tracy… - Fetal Diagnosis and …, 2021 - karger.com
Purpose: We examined select pulmonary effects and donor cell kinetics after transamniotic
stem cell therapy (TRASCET) in a model of congenital diaphragmatic hernia (CDH) …

VEGFR-3 signaling in macrophages: friend or foe in disease?

S Kannan, JM Rutkowski - Frontiers in Immunology, 2024 - frontiersin.org
Lymphatic vessels have been increasingly appreciated in the context of immunology not
only as passive conduits for immune and cancer cell transport but also as key in local tissue …

The role of growth factors in the pathogenesis of dengue: a scoping review

VE Fiestas Solórzano, RC de Lima, EL de Azeredo - Pathogens, 2022 - mdpi.com
Growth factors (GFs) have a role in tissue repair and in the modulation of the expression of
inflammatory cells in damage caused by pathogens. This study aims to systematize the …

Reduced vascular endothelial growth factor levels in the cerebrospinal fluid in patients with treatment resistant major depression and the effects of electroconvulsive …

L Kranaster, K Blennow, H Zetterberg… - Journal of affective …, 2019 - Elsevier
Background Several lines of evidence are pointing towards an involvement of the vascular
endothelial growth factor (VEGF) in the pathophysiology of depression. There are studies …

Congenital diaphragmatic hernia as a potential target for transamniotic stem cell therapy

AV Chalphin, SA Tracy, SP Lazow, I Kycia… - Journal of Pediatric …, 2020 - Elsevier
Purpose We sought to determine whether TRASCET could impact congenital diaphragmatic
hernia (CDH). Methods Twelve pregnant dams received Nitrofen on gestational day 9.5 (E9; …

[HTML][HTML] The consequence of endothelial remodelling on the blood spinal cord barrier and nociception

A Younis, L Hardowar, S Barker, RP Hulse - Current Research in …, 2022 - Elsevier
Nociception is a fundamental acute protective mechanism that prevents harm to an
organism. Understanding the integral processes that control nociceptive processing are …