Antibiotics have become the corner stone of modern medicine. However, our society is
currently facing one of the greatest challenges of its time: the emergence of antimicrobial …

Microbial cells show a strong natural tendency to adhere to surfaces and to colonize them by
forming complex communities called biofilms. In this growth mode, biofilm-forming cells …

The increasing prevalence of multidrug-resistant (MDR) Klebsiella pneumoniae is a serious
clinical and public health problem, and colistin is the last-resort treatment option for MDR …

Infectious disease caused by pathogenic bacteria continues to be the primary challenge to
humanity. Antimicrobial resistance and microbial biofilm formation in part, lead to treatment …

The aim of the present work was to investigate the antibacterial, antibiofilm, and antiquorum
sensing activities of phytosynthesized silver nanoparticles (AgNPs) fabricated from Mespilus …

Carbapenem-resistant Klebsiella pneumoniae (CR-Kp) can cause biofilm-related
bloodstream infections associated with significant morbidity and mortality worldwide. We …

The design and development of novel antibacterial and/or antifungal lead structures are
urgently required to cope with the increasing antimicrobial resistance. Inspired by the …

Colistin is used as a last resort for the management of infections caused by multi-drug
resistant (MDR) bacteria. However, the use of this antibiotic could lead to different side …

Our previous studies have revealed that the aminated 1, 4-quinone scaffold can be used for
the development of novel antibacterial and/or antifungal agents. In this study, the aminated …

Rapid identification and characterization of multidrug-resistant Klebsiella pneumoniae
strains is essential to diagnose severe infections in patients. In clinical routine practice, K …