Translating mesenchymal stem cell and their exosome research into GMP compliant advanced therapy products: Promises, problems and prospects

CY Ma, Y Zhai, CT Li, J Liu, X Xu… - Medicinal Research …, 2024 - Wiley Online Library
Mesenchymal stem cells (MSCs) are one of the few stem cell types used in clinical practice
as therapeutic agents for immunomodulation and ischemic tissue repair, due to their unique …

Engineering considerations of iPSC-based personalized medicine

S Park, Y Gwon, SA Khan, KJ Jang, J Kim - Biomaterials Research, 2023 - spj.science.org
Personalized medicine aims to provide tailored medical treatment that considers the clinical,
genetic, and environmental characteristics of patients. iPSCs have attracted considerable …

MgO nanoparticles-incorporated PCL/gelatin-derived coaxial electrospinning nanocellulose membranes for periodontal tissue regeneration

W Peng, S Ren, Y Zhang, R Fan, Y Zhou… - … in Bioengineering and …, 2021 - frontiersin.org
Electrospinning technique has attracted considerable attention in fabrication of cellulose
nanofibrils or nanocellulose membranes, in which polycaprolactone (PCL) could be used as …

Stem cell treatment for knee articular cartilage defects and osteoarthritis

A Arshi, FA Petrigliano, RJ Williams… - Current reviews in …, 2020 - Springer
Abstract Purpose of Review To review the current basic science and clinical literature on
mesenchymal stem cell (MSC) therapy for articular cartilage defects and osteoarthritis of the …

Extracellular vesicles derived from human embryonic stem cell‐MSCs ameliorate cirrhosis in thioacetamide‐induced chronic liver injury

S Mardpour, SN Hassani, S Mardpour… - Journal of cellular …, 2018 - Wiley Online Library
Various somatic tissue‐derived mesenchymal stromal cells (MSCs) have been considered
as an attractive therapeutic tool for treatment of liver diseases in which the secretion of …

Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury

SZ Seyedrazizadeh, S Poosti, A Nazari… - Stem cell research & …, 2020 - Springer
Background Retinal and/or optic nerve injury is one of the leading causes of blindness due
to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress …

Dental Tissue− derived mesenchymal stem cells: applications in tissue engineering

JR Dave, GB Tomar - Critical Reviews™ in Biomedical …, 2018 - dl.begellhouse.com
In recent years, mesenchymal stem cells (MSCs) derived from dental tissue have gained in
popularity for tissue-engineering and regenerative medicine applications. The highly …

[HTML][HTML] Application of mesenchymal stem cells derived from human pluripotent stem cells in regenerative medicine

TM Liu - World Journal of Stem Cells, 2021 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) represent the most clinically used stem cells in
regenerative medicine. However, due to the disadvantages with primary MSCs, such as …

[HTML][HTML] Modified mesenchymal stem cells in cancer therapy: A smart weapon requiring upgrades for wider clinical applications

C Vicinanza, E Lombardi, F Da Ros… - World journal of stem …, 2022 - ncbi.nlm.nih.gov
Mesenchymal stem stromal cells (MSC) are characterized by the intriguing capacity to home
toward cancer cells after systemic administration. Thus, MSC can be harnessed as targeted …

Detection, characterization, and clinical application of mesenchymal stem cells in periodontal ligament tissue

A Tomokiyo, S Yoshida, S Hamano… - Stem Cells …, 2018 - Wiley Online Library
Mesenchymal stem cells (MSCs) are a kind of somatic stem cells that exert a potential to
differentiate into multiple cell types and undergo robust clonal self‐renewal; therefore, they …