Long‐term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy

J Desloovere, P Boon, LE Larsen, C Merckx… - …, 2019 - Wiley Online Library
Objective More than one‐third of patients with temporal lobe epilepsy (TLE) continue to have
seizures despite treatment with antiepileptic drugs, and many experience severe drug …

DREADDs: the power of the lock, the weakness of the key. Favoring the pursuit of specific conditions rather than specific ligands

R Goutaudier, V Coizet, C Carcenac, S Carnicella - ENeuro, 2019 - eneuro.org
DREADDs (designer receptors exclusively activated by designer drugs) are a powerful and
tremendous new technique for selectively manipulating a specific neuronal (or non …

Dopaminergic control of striatal cholinergic interneurons underlies cocaine-induced psychostimulation

RG Lewis, M Serra, D Radl, M Gori, C Tran… - Cell reports, 2020 - cell.com
Cocaine drastically elevates dopamine (DA) levels in the striatum, a brain region that is
critical to the psychomotor and rewarding properties of the drug. DA signaling regulates …

Chemogenetic inhibition of the amygdala modulates emotional behavior expression in infant rhesus monkeys

J Raper, L Murphy, R Richardson, Z Romm… - Eneuro, 2019 - eneuro.org
Manipulation of neuronal activity during the early postnatal period in monkeys has been
largely limited to permanent lesion studies, which can be impacted by developmental …

Combining designer receptors exclusively activated by designer drugs and neuroimaging in experimental models: A powerful approach towards neurotheranostic …

LM Peeters, S Missault, AJ Keliris… - British Journal of …, 2020 - Wiley Online Library
The combination of chemogenetics targeting specific brain cell populations with in vivo
imaging techniques provides scientists with a powerful new tool to study functional neural …

[图书][B] Isoforms, Clocks, and Acetylcholine: Regulation of Cocaine's Effectsby Dopamine D2 Receptors

RG Lewis - 2022 - search.proquest.com
Cocaine is a highly addictive stimulant which immensely raises dopamine levels in brain
areas controlling motor and reward functions. Dopamine signaling is controlled by the five …

[PDF][PDF] Combining DREADDs and neuroimaging in experimental models: a powerful approach towards neurotheranostic applications

LM Peeters - Unraveling the interplay of brain networks …, 2020 - repository.uantwerpen.be
The combination of chemogenetics targeting specific brain cell populations with invivo
imaging techniques provides scientists with a powerful new tool to study functional neural …

10 Lessons Learned about

CBM Araujo, M Vergara - Neuron Signaling in Metabolic …, 2021 - books.google.com
Interoception refers to the process by which the nervous system senses and integrates
signals originating from within the body [1]. The vagus nerve is a critical neural pathway for …

Lessons Learned about Metabolism from Traditional and Novel Tools for Studying the Structure and Function of the Vagus Nerve

G de Lartigue, A Singh, A de Araujo… - Neuron Signaling in …, 2021 - taylorfrancis.com
The vagus nerve is a critical neural pathway for conveying information about the internal
condition of the body to the brain. Here the authors discuss how the tools we have at our …

10 Lessons Learned about Metabolism

G de Lartigue, A Singh, A de Araujo… - Neuron Signaling in …, 2021 - books.google.com
10.3. 2.2 Selective Vagotomy 10.3. 2.3 Capsaicin 10.3. 2.4 Subdiaphragmatic
Deafferentation 10.3. 2.5 What We Have Learned from Approaches Inhibiting the Vagus …