Inflammatory bowel disease (IBD) is a chronic, inflammatory, and autoimmune disorder. The
pathogenesis of IBD is not yet clear. Studies have shown that the imbalance between T …

Inflammatory bowel disease (IBD) is an umbrella term for the chronic immune-mediated
idiopathic inflammation of the gastrointestinal tract, manifesting as Crohn's disease (CD) or …

As a main digestive organ and an important immune organ, the intestine plays a vital role in
resisting the invasion of potential pathogens into the body. Intestinal immune dysfunction …

In 2018, the pan-Janus kinase (JAK) inhibitor tofacitinib was launched for the treatment of
ulcerative colitis (UC). Although tofacitinib has proven efficacious in patients with active UC …

Foreign body response (FBR) to biomaterials compromises the function of implants and
leads to medical complications. Here, we report a hybrid alginate microcapsule (AlgXO) that …

Tissue repairing capacity and immunomodulatory effects of mesenchymal stem cells (MSCs)
have been extensively utilized for treating various inflammatory disorders; however …

Enteric-coated formulations using Eudragit® polymers have been extensively used for
delivering drugs to the lower gastrointestinal tract. However, these drug-delivery systems …

Inflammatory bowel disease (IBD) is a long-lasting and inflammatory autoimmune condition
affecting the gastrointestinal tract, impacting millions of individuals globally. The balance …

Blocking the mevalonate pathway for cholesterol reduction by using statin may have
adverse effects including statin‐induced colitis. Moreover, one of the predisposing factors for …

Abstract Bryostatin‐1 (Bry‐1) has been proven to be effective and safe in clinical trials of a
variety of immune‐related diseases. However, little is known about its effect on Crohn's …