Circular RNAs: emblematic players of neurogenesis and neurodegeneration

M D'Anca, FR Buccellato, C Fenoglio… - International journal of …, 2022 - mdpi.com
In the fascinating landscape of non-coding RNAs (ncRNAs), circular RNAs (circRNAs) are
peeping out as a new promising and appreciated class of molecules with great potential as …

Microtubule plus-end tracking proteins in neuronal development

D van de Willige, CC Hoogenraad… - Cellular and Molecular …, 2016 - Springer
Regulation of the microtubule cytoskeleton is of pivotal importance for neuronal
development and function. One such regulatory mechanism centers on microtubule plus …

Multivalency ensures persistence of a+ TIP body at specialized microtubule ends

SM Meier, AM Farcas, A Kumar, M Ijavi, RT Bill… - Nature Cell …, 2023 - nature.com
Microtubule plus-end tracking proteins (+ TIPs) control microtubule specialization and are as
such essential for cell division and morphogenesis. Here we investigated interactions and …

Characterization of distinct circular RNA signatures in solid tumors

C Wang, WR Liu, S Tan, JK Zhou, X Xu, Y Ming… - Molecular Cancer, 2022 - Springer
Abstract Background Circular RNAs (circRNAs) are differentially expressed between normal
and cancerous tissues, contributing to tumor initiation and progression. However …

Mapping autosomal recessive intellectual disability: combined microarray and exome sequencing identifies 26 novel candidate genes in 192 consanguineous families

R Harripaul, N Vasli, A Mikhailov, MA Rafiq… - Molecular …, 2018 - nature.com
Approximately 1% of the global population is affected by intellectual disability (ID), and the
majority receive no molecular diagnosis. Previous studies have indicated high levels of …

Differentially expressed circular RNAs in peripheral blood mononuclear cells of patients with Parkinson's disease

S Ravanidis, A Bougea, D Karampatsi… - Movement …, 2021 - Wiley Online Library
Background New noninvasive and affordable molecular approaches that will complement
current practices and increase the accuracy of Parkinson's disease (PD) diagnosis are …

Control of apico–basal epithelial polarity by the microtubule minus-end-binding protein CAMSAP3 and spectraplakin ACF7

I Noordstra, Q Liu, W Nijenhuis, S Hua… - Journal of cell …, 2016 - journals.biologists.com
The microtubule cytoskeleton regulates cell polarity by spatially organizing membrane
trafficking and signaling processes. In epithelial cells, microtubules form parallel arrays …

Cytoskeletal social networking in the growth cone: How+ TIPs mediate microtubule‐actin cross‐linking to drive axon outgrowth and guidance

GM Cammarata, EA Bearce, LA Lowery - Cytoskeleton, 2016 - Wiley Online Library
The growth cone is a unique structure capable of guiding axons to their proper destinations.
Within the growth cone, extracellular guidance cues are interpreted and then transduced …

Tau, XMAP215/Msps and Eb1 co-operate interdependently to regulate microtubule polymerisation and bundle formation in axons

I Hahn, A Voelzmann, J Parkin, JB Fülle, PG Slater… - PLoS …, 2021 - journals.plos.org
The formation and maintenance of microtubules requires their polymerisation, but little is
known about how this polymerisation is regulated in cells. Focussing on the essential …

TIPsy tour guides: how microtubule plus-end tracking proteins (+ TIPs) facilitate axon guidance

EA Bearce, B Erdogan, LA Lowery - Frontiers in cellular neuroscience, 2015 - frontiersin.org
The growth cone is a dynamic cytoskeletal vehicle, which drives the end of a developing
axon. It serves to interpret and navigate through the complex landscape and guidance cues …