[HTML][HTML] Serious adverse events after cessation of nucleos (t) ide analogues in individuals with chronic hepatitis B: A systematic review and meta-analysis

CH Tseng, TH Chen, JL Wu, TY Lee, JA Borghi, JT Lin… - JHEP Reports, 2023 - Elsevier
Background & Aims The risk of serious clinical outcomes following cessation of nucleos (t)
ide analogues (NUCs) in individuals with chronic hepatitis B remains poorly characterized …

Guidelines for the prevention and treatment of chronic hepatitis B (version 2022)

H You, FS Wang, T Li, X Xu, Y Sun, Y Nan… - Infectious Diseases & …, 2023 - mednexus.org
To facilitate the achieving of the goal of" eliminating viral hepatitis as a major public health
threat by 2030" set by the World Health Organization, the Chinese Society of Hepatology …

[HTML][HTML] Health inequalities in the management of chronic hepatitis B virus infection in patients from sub-Saharan Africa in high-income countries

T Mitchell, JS Nayagam, G Dusheiko, K Agarwal - JHEP Reports, 2023 - Elsevier
Chronic hepatitis B virus disproportionately affects migrant communities in high-income
countries, reflecting increased migration from sub-Saharan Africa. Chronic hepatitis B virus …

[HTML][HTML] A case of HBV-induced liver failure in the REEF-2 phase II trial: Implications for finite treatment strategies in HBV 'cure'

K Agarwal, J Lok, I Carey, Y Shivkar, M Biermer… - Journal of …, 2022 - Elsevier
Nucleoside analogues are the mainstay of treatment for patients with chronic HBV infection
but have no direct effect on covalently closed circular DNA. Long-term HBV viral …

Stopping nucleot (s) ide analogues in non‐cirrhotic HBeAg‐negative chronic hepatitis B patients: HBsAg loss at 96 weeks is associated with low baseline HBsAg …

SAL Hall, GS Burns, D Anagnostou… - Alimentary …, 2022 - Wiley Online Library
Summary Background and Aims Current guidelines recommend long‐term nucleot (s) ide
analogue (NA) therapy for patients with HBeAg‐negative chronic hepatitis B (CHB) …

Severe hepatitis B flares with hepatic decompensation after withdrawal of nucleos (t) ide analogues: a population‐based cohort study

YC Hsu, YH Lin, TY Lee, MH Nguyen… - Alimentary …, 2023 - Wiley Online Library
Background Finite nucleos (t) ide analogue (NUC) therapy has been proposed as an
alternative treatment strategy for chronic hepatitis B (CHB). Aim To quantify the incidence of …

[HTML][HTML] Safety considerations for withdrawal of nucleos (t) ide analogues in patients with chronic hepatitis B: First, do no harm

YC Hsu, CH Tseng, JH Kao - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Nucleos (t) ide analogues (NA) are widely used to treat hepatitis B virus (HBV) infection, but
they cannot eradicate the virus and treatment duration can be lifelong if the endpoint is set at …

Emerging therapies for chronic hepatitis B and the potential for a functional cure

ML Chang, YF Liaw - Drugs, 2023 - Springer
Worldwide, an estimated 296 million people are living with chronic hepatitis B virus (HBV)
infection, with a significant risk of morbidity and mortality. Current therapy with pegylated …

[HTML][HTML] KASL clinical practice guidelines for management of chronic hepatitis B

Korean Association for the Study of the … - Clinical and …, 2022 - ncbi.nlm.nih.gov
Chronic hepatitis B (CHB) is a major cause of chronic liver diseases in Korea and remains a
threat to public health due to its high morbidity and disease-related mortality. Since the latest …

novel biomarkers in hepatitis B infection

J Lok, G Dusheiko, I Carey… - Alimentary Pharmacology …, 2022 - Wiley Online Library
Background Chronic hepatitis B remains a global health problem with an estimated 296
million people affected worldwide. Individuals are at risk of serious complications such as …